Wenhao Wu, Wen Lei, Liqiong Wang, Sen Wang, Haijun Zhang. Preparation of Single Atom Catalysts[J]. Progress in Chemistry, 2020, 32(1): 23-32.
Single atom catalysts, as catalysts with atomic scale, have a wide range of applications in the fields of hydrogen production, CO oxidation, photocatalysts, etc. Extensive efforts of experimental/theoretical studies show that the strong metal support interactions and the changes in electronic structure are the main reasons for the high selectivity and catalytic activity of the single atom catalysts. This paper mainly summarizes the recent researches on the preparation methods including coprecipitation method, successive reduction method and wet-impregnation method, catalytic performance and high catalytic selectivity of single atom catalysts. And finally, the prospects for future investigations of single atom catalysts are proposed.
Quanchao Zhuang, Zi Yang, Lei Zhang, Yanhua Cui. Research Progress on Diagnosis of Electrochemical Impedance Spectroscopy in Lithium Ion Batteries[J]. Progress in Chemistry, 2020, 32(6): 761-791.
Electrochemical impedance spectroscopy (EIS) is one of the most powerful experimental methods to study electrochemical systems, and has been extensively used in the analysis of lithium battery systems, especially to determine kinetic and transport parameters, understand reaction mechanisms, and to study degradation effects in past two decades. In this paper, the electrode polarization process in lithium ion batteries which includes three basic physical and chemical processes, namely, electronic transport process, ionic transport process and electrochemical reaction process, is briefly described, and the EIS characteristics of each transport and reaction stage of the three basic physical and chemical processes are discussed, especially the mechanism of inductance formation and contact impedance is expounded in detail. Moreover, porous electrode theory and its application in lithium ion batteries are reviewed, and emphasis is put upon the principle and method of numerical simulation of impedance with physics-based lithium-ion batteries models. Furthermore, the typical EIS characteristics and the attribution of each time constant of the electrode materials for lithium ion batteries such as graphite, silicon, simple binary transition metal oxides, LiCoO2, spinel LiMn2O4, LiFePO4, spinel Li4Ti5O12 and transition metal oxides are also discussed. Finally, the challenges currently faced by EIS are identified and possible directions and approaches in addressing these challenges are suggested.
Contents
2.1 Schottky contact impedance
2.2 The mechanism of inductance formation
2.3 Porous electrode theory and numerical simulation of impedance and their applications in lithium ion batteries
3.1 The EIS characteristics of lithium ion battery anode
3.2 The EIS characteristics of lithium ion battery cathode
Xinzhi Wang, Hongli Wang, Feng Shi. Alcohol Amination for N-Alkyl Amine Synthesis with Heterogeneous Catalysts[J]. Progress in Chemistry, 2020, 32(2/3): 162-178.
N-alkyl amines are an important class of molecules in the chemical industry and are extensively applied in the syntheses of dyes, pharmaceuticals, agrochemicals, surfactants, rubber ingredients, and functional materials. Given the importance of N-alkyl amines, the development of efficient synthetic methodologies to synthesize these amines is of broad interest. Among various methods, the catalytic alcohol amination has been viewed as effective and green method for synthesis of N-alkyl amines because alcohol is readily available, and water is generated as the sole by-product. This review describes developments and recent advances in the alcohol amination with different heterogeneous catalyst systems, including nickel, copper, palladium, platinum, cobalt, manganese, iron, gold, ruthenium, silver, and other catalyst systems. The frontiers and future of the topic are also given.
Kai Han, Nuo Li, Hongqi Ye, Kai Han*. Synthesis of Two-Dimensional MXene and Their Applications in Electrochemical Energy Storage[J]. Progress in Chemistry, 2018, 30(7): 932-946.
Sun Bing, Ai Shiyun. Fabrication and Application of Photoelectrochemical Sensor[J]. Progress in Chemistry, 2014, 26(05): 834-845.
Photoelectrochemical sensor is a dynamically developed and promising analytical method, based on the photoelectrochemical process and chemical or biological probing recognition. Benefitting from the separation of the excitation source (light) and electrochemical detection signal (photocurrent), the photoelectrochemical sensor possesses many intrinsic advantages, such as higher sensitivity with low background signals, simpler and low-cost instruments, and inherent miniaturization. It has received an increasing attention and shows an extensive application potential in rapid and high-throughput biological and chemical assays. Under light irradiation, the photocurrent is recorded on the basis of the electron transfer among the photoelectrochemical materials in excited state, electrode surface, and electrolyte. Depending on the photocurrent change resulting from the interactions between various sensing elements and their target analytes, the quantitative photocurrent-analyte relationship is obtained. There are two key portions in the development of photoelectrochemical sensor: the fabrication of the photosensitive layer and the assembly of the molecular recognition layer at the transducer surface. The design and fabrication of photosensitizer, deriving from photoelectrochemically active species and the exploitation of exquisite sensing mechanisms are of extreme importance in the achievements of acceptable sensitivity. In this paper, the sensing principle of photoelectrochemical sensor, lasted applications, design and fabrication of photosensitizer and developments of sensing strategies are reviewed.
Contents 1 Photoelectrochemistry and photoelectrochemical process 2 Introduction to photoelectrochemical sensor 3 Photoelectrochemically active species for the design and fabrication of photoelectrochemical sensor 3.1 Organic photovoltaic molecule 3.2 Conducting polymer 3.3 Inorganic semiconductor and its composites 3.4 Other photovoltaic materials 4 Signal generating mechanism and sensing strategies 4.1 Direct charge transmission and redox reaction 4.2 Signal-off strategy derived from steric hindrance based on molecular recognition 4.3 Enzymatic inhibition and enzymatic catalysis 4.4 Local surface plasma resonance (LSPR) of noble metal nanoparticles and energy transfer in exciton-plasmon interaction (EPI) 4.5 Other probing strategies 5 Prospective of photoelectrochemical sensor
Jianlei Qi, Qinqin Xu, Jianfei Sun, Dan Zhou, Jianzhong Yin. Synthesis, Characterization and Analysis of Graphene-Supported Single-Atom Catalysts[J]. Progress in Chemistry, 2020, 32(5): 505-518.
Single-atom catalyst has the advantages of low coordination number, special coordination environment, high atomic utilization, and high uniformity of catalytic sites. It is the bridge between homogeneous and heterogeneous catalysts, which helps to better understand the nature of catalytic reaction. In this paper, the synthetic methods of graphene-based single-atom catalysts in recent years are reviewed, including atomic layer deposition, impregnation-calcination, defect trapping, coordination anchoring and some other novel methods, with a focus on the preparation process, principle and characterization results of these methods. Based on this, the performance of graphene-based metal single-atom catalysts in catalysis is illustrated and analyzed, and the purpose is to provide guidance and reference for the preparation of single-atom catalysts.
1 Introduction
2 Synthetic method
2.1 Atomic layer deposition method
2.2 Impregnation-calcination method
2.3 Defect trapping method
2.4 Coordination anchoring method
2.5 Other methods
3 Performance evaluation and characterization
3.1 Hydrogen evolution reaction
3.2 Carbon dioxide reduction reaction
3.3 Oxidation reaction
3.4 Hydrogenation reaction
4 Conclusion and outlook
Kerui Chen, Xin Hu, Jiangkai Qiu, Ning Zhu, Kai Guo. Synthesis of Bottlebrush Polymers by Ring-Opening Metathesis Polymerization[J]. Progress in Chemistry, 2020, 32(1): 93-102.
Bottlebrush polymers are a class of comb polymers that have the unique side chain structures and properties. Functional bottlebrush polymers have found broad applications in photonic crystals, surfactants, pharmaceutical carriers, antifouling coatings and smart materials. The synthetic strategies to bottlebrush polymers by ring-opening metathesis polymerization (ROMP) exhibit various advantages, such as simple synthesis steps, high polymer graft density and uniform side chain composition. Well control of polymer composition, molecular weight and molecular weight dispersity could be achieved by ROMP. This review summarizes the synthesis of homo, block, Janus, core-shell bottlebrush copolymers via ROMP. Moreover, the advances in finely controlling the bottlebrush polymer architecture are discussed.
Fenya Guo, Hongwei Li, Mengzhe Zhou, Zhengqi Xu, Yueqing Zheng, Tingting Li. Electroreduction of Nitrogen to Ammonia Catalyzed by Non-Noble Metal Catalysts under Ambient Conditions[J]. Progress in Chemistry, 2020, 32(1): 33-45.
Ammonia is an important chemical for producing fertilizer and also an important carbon-free energy carrier. Haber-Bosch process is the main method to synthesize ammonia. However, it suffers from some severe problems, such as the high energy consumption, the massive emission of greenhouse gas CO2 and the poor catalytic efficiency. Recently, ammonia synthesis based on electrocatalytic nitrogen reduction reaction (NRR) by using renewable energy under mild reaction conditions has attracted wide research attention. In addition, the raw materials (N2 + H2O) are earth abundant. Although great advances have been achieved in electrocatalytic NRR field, some challenges including the high-cost of noble metal based electrocatalysts, the low ammonia yield and unsatisfactory Faradaic efficiency, as well as the unexplored catalytic mechanism of NRR still exist. In this review, we summarize the recent advances in electrocatalytic NRR field based on heterogeneous catalysts. Firstly, we discuss the catalytic thermodynamics and reaction mechanisms towards NRR. Secondly, a range of recently reported non-noble metal included catalysts are surveyed, including transition metal oxides/nitrides/sulfides, metal-free materials and single-metal-atom catalysts. Then, some promising strategies to enhance the catalytic activity, selectivity and efficiency are proposed, and the main methods for the determination of ammonia are also mentioned. Finally, the challenges remaining to be solved are summarized, and future perspectives are also presented.
Xiaochun Tian, Xue'e Wu, Feng Zhao, Yanxia Jiang, Shigang Sun. Research on Mechanisms of Microbial Extracellular Electron Transfer by Electrochemical Integrated Technologies[J]. Progress in Chemistry, 2018, 30(8): 1222-1227.
Yongjie Zhang, Mingshuai Fan, Xiaopei Li, Huayi Li, Shuwei Wang, Wenqin Zhu. Silicon-Containing Functionalized Polyolefin: Synthesis and Application[J]. Progress in Chemistry, 2020, 32(1): 84-92.
Functionalization of polyolefin is an efficient route to new polymer materials with high performance/price ratio. Silicon-containing functional polyolefin (SFPO) is a kind of functional polyolefin that incorporate functional silicone groups or polysiloxane segments in the structure of polyolefin. Due to special physiochemical properties of silicone groups or polysiloxane, SFPO often possesses reactivity or advanced properties and forms a new group of functional polyolefin. SFPO can function as reactive intermediates in synthesizing functional polyolefins with complex topologies (star polymer, brush polymer and graft copolymer) or preparing polyolefin covalently grafted nanomaterials. SFPO can also serve as functional additives (compatibilizer, polymer process aid and surface modifier) in developing new polyolefin materials. In recent years, researchers have obtained a series of fruitful results on the syntheses and applications of SFPO. This review aims to cover the recent progress on SFPO, which we hope may arouse the attention of related researchers and promote further achievements in related research areas.
Xinxin Jiang, Chengjun Zhao, Chunju Zhong, Jianping Li*. The Electrochemical Sensors Based on MOF and Their Applications[J]. Progress in Chemistry, 2017, 29(10): 1206-1214.
Zhu Debin*, Ma Wenge, Xing Xiaobo . Application of Electrochemiluminescence Assay in Nucleic Acid Detection[J]. Progress in Chemistry
Rao Honghong, Xue Zhonghua, Wang Xuemei, Zhao Guohu, Hou Huihui, Wang Hui. Electrochemical Sensors Based on Electrochemically Reduced Graphene Oxide[J]. Progress in Chemistry, 2016, 28(2/3): 337-352.
Contents 1 Introduction 2 Preparation of ERGO modified electrodes 2.1 Indirect electrochemically reduced method 2.2 Direct electrochemically reduced method 3 Classification of ERGO modified electrodes 3.1 Intrinsical ERGO modified electrodes 3.2 The composite modified electrodes based on inorganic nanoparticles and ERGO 3.3 The composite modified electrodes based on organic compounds and ERGO 3.4 The composite modified electrodes based on inorganic-organic and ERGO 4 Electrocatalytic and electrochemical applications of ERGO modified electrodes 4.1 Electrochemical analysis of small molecules 4.2 Electrochemical analysis of molecules containing aromatic structure 4.3 Electrochemical analysis of biological molecules (protein and DNA) 5 Conclusion and outlook
Xiaoyan Wei, Gang Wang*, Anfeng Li, Yizhou Quan, Jinwei Chen, Ruilin Wang*. Application of Electrochemical Quartz Crystal Microbalance[J]. Progress in Chemistry, 2018, 30(11): 1701-1721.
Tong Wang, Wenjiao Zhao, Liangchun Li, Renlin Zheng, Dequn Sun. Synthesis of Dehydroamino Acids and Their Applications in the Drug Research and Development[J]. Progress in Chemistry, 2020, 32(1): 55-71.
Traditional polypeptides usually have the disadvantages of easy hydrolyzation, poor cell membrane permeability, and unstable conformation, which limits their application as a drug in the field of disease treatment. The conformational restriction caused by incorporation of dehydroamino acids into polypeptide can effectively improve the metabolic stability and bioavailability of peptides. In this paper, the synthesis methods and the recent applications in drug design of four kinds of dehydroamino acids including α,β-dehydro-α-amino acids, β,γ-dehydro-α-amino acids, α-dehydro-β-amino acids and α,β-dehydro-β-amino acids are reviewed, which could provide reference for the related research.
Song Yingpan, Feng Miao, Zhan Hongbing*. Application of Graphene Edge Effect in Electrochemical Biosensors[J]. Progress in Chemistry, 2013, 25(05): 698-706.
The unique structure of basal planes and edges in graphene endows graphene specific properties, such as the much higher heterogeneous electron transfer rate, capacitance, local density of states and structural defects, functional groups of edges than basal planes. These inherent features of graphene, which have a great role in promoting its electrochemical performance, are the embodiment of the edge effect. This paper introduces the influence of edge effect on the electrochemical performance of graphene, gives a review and prospect of graphene with different morphology characteristics, such as graphene nanoflakes, nanosheets, nanoplatelets, nanowalls, nanofibers, nanoribbons, and quantum dots, applying in the electrochemical biosensing field. Contents 1 Introduction 2 Edge effect of electrochemical performances: from graphite to graphene 2.1 Edge effect of electrochemical performances in graphite 2.2 Edge effect of electrochemical performances in graphene 3 Two- and quasi two-dimensional graphene-based electrochemical biosensors 4 One- and zero-dimensional graphene-based electr-ochemical biosensors 5 Conclusion and prospect
Liu Lidan, Xiao Yong, Wu Yicheng, Chen Bilian, Zhao Feng. Electron Transfer Mediators in Microbial Electrochemical Systems[J]. Progress in Chemistry, 2014, 26(11): 1859-1866.
Extracellular electron transfer (EET) between electrochemically active microorganisms and electrodes plays a key role in microbial electrochemical systems (MESs) functioning of energy generation, bioremediation, etc. At present, researchers have a very limited understanding of the mechanism of EET, which is one of the major bottlenecks in application of MESs. Compared with direct electron transfer which requires a direct contact between microbial functional proteins and electrode, mediated electron transfer use electron transfer mediators (ETMs) which have reversible redox activities accompanies by high-efficiency EET for transporting electrons. ETMs serve as the middle electron acceptor, once reduced, can transfer electrons to terminal electron acceptor where upon it becomes re-oxidized. In principle, ETMs molecules could cycle thousands of times,thus, have a significant effect on the turnover of the terminal oxidant (e.g.iron) in certain circumstances.This review summarizes the recent advances of EET mechanisms with focus on mediated EET in MESs. Furthermore, we have highlighted the research trends of ETMs in MES,which will promote the practical applications of MESs in bioremediation, energy generation and so on.
Contents 1 Introduction 2 Roles of electron transfer mediators in extracellular electron transfer 3 Properties of electron transfer mediators 4 Classification of electron transfer mediators 5 Electron transfer mediators and their electron transfer mechanism 5.1 Exogenous electron transfer mediators 5.2 Endogenous electron transfer mediators 6 Outlook
Feng Xiaomiao, Li Ruimei, Yang Xiaoyan, Hou Wenhua. Application of Novel Carbon Nanomaterials to Electrochemistry[J]. Progress in Chemistry
Kang Yiran, Cai Feng, Chen Hongyuan, Chen Minghai, Zhang Rui, Li Qingwen. Carbon Nanotube/Graphene Hybrid Nanostructures and Their Application in Supercapacitors[J]. Progress in Chemistry, 2014, 26(09): 1562-1569.
In this paper, we review the preparation methods of carbon nanotube (CNT)/graphene composite materials for the electrode of supercapacitors, and introduce the developments of CNT/graphene/pseudo-capacitive material ternary composite materials with highly electrochemical performance. The rational designed CNT/graphene composite nanostructures could largely utilize the characteristics of carbon nanomaterials for electrochemical double-large supercapacitors, such as large specific area, high conductivity and befitting porous structure, and also achieve large mass loading of pseudo-capacitive materials with high dispersion for pseudo-capacitors. As a result, these composite materials are promising candidates for the electrode materials of high-performance supercapacitors with high capacitance, excellent rate performance and long lifetime.
Contents 1 Introduction 2 The preparation strategies of carbon nanotube/graphene composites 2.1 The assembling based on π-π interaction 2.2 The assembling based on electrostatic attraction 2.3 In-situ growth 2.4 Other methods 3 Ternary composite electrodes based on graphene, carbon nanotube and pseudo-capacitive materials 3.1 Carbon nanotube/graphene/conductive polymer 3.2 Carbon nanotube/graphene/metallic oxides (hydroxides) 4 Conclusion
Xiao Yong, Wu Song, Yang Zhaohui, Zheng Yue, Zhao Feng. Isolation and Identification of Electrochemically Active Microorganisms[J]. Progress in Chemistry, 2013, 25(10): 1771-1780.
Bioelectrochemical system (BES), in which electrode reaction is driven by electrochemically active microorganisms (EAM) to recovery energy, degrade contaminants and synthesize high additional value compounds, is a promising biotechnology. EAM is the basis of BES, microorganisms-electrode interaction plays a key role in BES functioning. In contrast with the expanding of BES function, especially BES cathode, the diversity of isolated EAM is limited, and most of them are applied in anode to generate a high power density. In addition, the understanding of microorganisms-electrode interaction mostly confines in Geobacter and Shewanella genus. In this article, we review medium, culture condition and microorganisms identification, as well as cyclic voltammetry, differential pulse voltammetry and chronoamperometry for the isolation and identification of EAMs. We further highlight the research trends of expanding EAM diversity and of microorganisms-electrode interaction, which would promote the application of BES in environmental control and bioenergy production.
Contents 1 Introduction 2 Electrochemically active microorganisms 3 Microorganism isolation 3.1 Culture medium 3.2 Culture condition 4 Microorganism biological identification 4.1 16S/18S rRNA gene sequencing and analysis 4.2 Morphological, physiological and biochemical characterization 5 Characterization of electrochemical activity 5.1 Cyclic voltammetry 5.2 Differential pulse voltammetry and square wave voltammetry 5.3 Chronoamperometry 6 Outlook
Li Liangjun, Jianhui Deng, Jianwei Guo, Hangbo Yue. Synthesis and Properties of Microporous Organic Polymers Based on Adamantane[J]. Progress in Chemistry, 2020, 32(2/3): 190-203.
Microporous organic polymers(MOPs) is one of the most promising new materials for many applications, such as gas capture and storage, gas separation, organic vapor adsorption, heterogeneous catalyst carrier, water treatment, functional materials and so on, making them to be a research hotspot. This is due to the fact that MOPs have shown many advantages in, for example, excellent thermal stability, chemical stability, low density, high specific surface area, and molecular pore size architecture. Generally, molecular building blocks, particularly being symmetrical in plane or space, are the core architecture in the synthesis of MOPs. Among various building molecules, multi-substituted adamantane, has been reported as a new molecular "knot" candidate for the creation of MOPs, by connecting with a "linkage" molecule, thanks to its highly stereoscopic symmetrical structure and structural rigidity. In addition, the adamantane-based MOPs have shown many advantageous and interesting properties in terms of synthetic yield, structural stability, pore size distribution, gas/vapor adsorption and separation. This mini review focuses on recent progress in the synthesis and interesting properties of the MOPs with adamantane incorporated(MOP-Ad). The MOP-Ad polymers are classified into phenyl-linkage, Schiff base linkage, imide linkage, and nitrogen-rich(benzimidazole and triazine) categories. Special attention is paid to the similarities and differences with comparison in the synthetic route, structural characteristics, stability and adsorption properties. Besides, some emerging new types of Ad-polymers are briefly introduced and an outlook is also proposed for the MOP-Ad.
Chenxi Liang, Lixin Cao*, Yuejuan Zhang, Peisheng Yan. Electrochemical Biosensors for Marine Toxins Analysis[J]. Progress in Chemistry, 2018, 30(7): 1028-1034.
Xing Liwen, Ma Zhanfang. Non-Enzymatic Electrochemical Sensors Based on Carbon Nanomaterials for Simultaneous Detection of Ascorbic Acid, Dopamine, and Uric Acid[J]. Progress in Chemistry, 2016, 28(11): 1705-1711.
Contents 1 Introduction 2 Carbon nanomaterials-based non-enzymatic electrochemical sensors for simultaneous detection of ascorbic acid, dopamine, and uric acid 2.1 One-dimensional carbon nanomaterials 2.2 Two-dimensional carbon nanomaterials 2.3 Zero-dimensional carbon nanomaterials 2.4 Three-dimensional carbon nanomaterials 3 Conclusion
He Huichao, Sean P. Berglund, Buddie Mullins, Zhou Yong, Ke Gaili, Dong Faqin. Scanning Electrochemical Microscopy for Photoelectrochemical Energy Research[J]. Progress in Chemistry, 2016, 28(6): 908-916.
Contents 1 Introduction 2 SECM operation modes 2.1 Feedback mode 2.2 Generation-collection mode 3 SECM used as tool for photoelectrochemical energy research 4 SECM used as screening technique for developing metal ion doped WO3 photocatalysts 5 Conclusion and outlook
Xiujun Cao, Lei Zhang, Yuanxin Zhu, Xin Zhang, Chaonan Lv, Changmin Hou. Design and Synthesis of Sillenite-Based Micro/Nanomaterials and Their Applications in Photocatalysis[J]. Progress in Chemistry, 2020, 32(2/3): 262-273.
The sillenite-based photocatalytic materials have attracted the researchers’ interests because of their unique crystal and electronic structures, as well as remarkable visible light absorption abilities. However, they usually have poor photocatalytic activities and stabilities owing to their structural and functional defects, such as high recombination efficiencies of photo-generated charges, low quantum yields, limited active sites, and insufficient exposure of active crystal planes. Therefore, how to achieve optimal modulation of photocatalytic activity and stability based on the structural design and functional integration of sillenite-based photocatalysts on the micro-nano scale is still a key scientific problem. This paper mainly reviews the synthesis strategies of sillenite-based micro/nanomaterials and their latest research progress in the field of photocatalysis, especially focusing on the morphology control, noble metal loading, semiconductor/graphene coupling, ion doping and the development of new sillenite-based photocatalytic systems. Moreover, the photocatalytic applications of sillenite materials are discussed. Finally, the future research prospects of such photocatalytic materials are also pointed out.
Miao Gong, Xiaoying Wang, Xiaoning Wang. Electrochemical Sensing Detection of Biomarkers in Hematological Malignancies[J]. Progress in Chemistry, 2019, 31(6): 894-905.
Hematological malignancies(HM) is a kind of malignant disease of hematology system which seriously threatens human health, mainly involving bone marrow, blood and lymphatic tissue. The quantification of biomarkers in hematological malignancies is the key for fine stratification analysis, personalized targeted therapy and prognostic improvement. In this paper, the specific types and the commonly used detection methods at home and abroad of the hematological malignancies related biomarkers are summarized and compared. Specifically, the latest application of new electrochemical biosensor for the hematological malignancies related biomarkers is mainly described. Furthermore, the summary of its future directions and the potential applications is given, which provides reference for the further research and application of the biomarkers in hematological malignancies.
Wu Yiping, Guo Lianghong. Photoelectrochemical Sensors for the Detection of DNA Damage[J]. Progress in Chemistry, 2014, 26(01): 1-9.
DNA is a kind of genetic material that encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses. DNA damage occurs frequently in organisms. Some endogenous and exogenous chemicals have been found to induce structural damages to nuclear DNA by base oxidation or modification. If unrepaired, these damaged DNA may lead to gene mutation and even tumor generation. Due to their short response time, high sensitivity, low cost and ease of miniaturization, electrochemical DNA sensors are well qualified for the rapid screening of industrial and environmental chemicals for their potential geno-toxicity. This review article first introduces briefly the types and working mechanisms of current electrochemical DNA sensors. Then it describes in more detail the work on electrochemical and photoelectrochemical sensors for the detection of DNA damage, based largely on the work of our own laboratory, including general type sensors for the rapid screening of industrial and environmental chemicals with potential geno-toxicity, as well as specific type sensors for the identification and quantification of DNA damage products such as 8-oxodGuo and methylated DNA bases. In the end, the existing problems and future research directions of the DNA damage electrochemical sensors are discussed.
Contents 1 Introduction 2 Types of DNA electrochemical sensors 3 Electrochemical sensors for DNA damage detection 4 Photoelectrochemical sensors for DNA damage detection 4.1 Photoelectrochemical detection method 4.2 Sensing mechanisms for DNA damage detection 4.3 General-type sensors 4.4 Specific-type sensors 4.5 Investigation of chemical-induced DNA damage 5 Conclusions and perspectives
Gao Feifei, Wang Yuebo. Electrochemical Detection of Protein Phosphorylation[J]. Progress in Chemistry, 2014, 26(05): 856-865.
The phosphorylation of proteins is a reversible post-translational modification, which is almost involved in all the life activities in organisms. Protein phosphorylation plays a significant role in specific genes expressing, cell proliferation and differentiation, especially in the further transduction of various life activities. Based on the changes of electrochemical signal, protein phosphorylation can be detected conveniently by electrochemical methods because of its high sensitivity and selectivity. This review summarizes several electrochemical methods for the detection of phosphorylation based on the electrode materials, and the common materials or molecules using for electrode modification. At the end of this review, the advantages and disadvantages, as well as a prospect of effective electrochemical detection of phosphorylation are given.
Contents 1 Introduction 2 The electrochemical detection for protein phosphorylation based on modified electrode 3 Several methods about electrode modification 3.1 Monolayer modified electrode 3.2 Multi molecular layer modified electrode 4 Several common modified electrodes used for electrochemical detection of protein phosphorylation 4.1 Electrochemical biosensor based on screen printed electrodes 4.2 Substrate peptide modified gold electrode 4.3 Glassy carbon electrodes 4.4 Indium tin oxide electrodes 4.5 Other modified electrodes 5 Conclusion and outlook
Li Qingchuan, Cao Lixin, Hu Haifeng, Wang Kai, Yan Peisheng. Electrochemical Biosensors for Aflatoxin Analysis[J]. Progress in Chemistry, 2014, 26(04): 657-664.
Aflatoxin is a kind of biotoxins with acute toxicity and strong carcinogenicity. Quick and accurate analysis is one of the most effective methods to minimize or avoid its hazard. Electrochemical biosensor has drawn widespread attention of domestic and foreign researchers for aflatoxin analysis,due to its rapidity,high degree of sensitivity and specificity, combined with its easiness to be miniaturized. So far, immunosensor, enzyme sensor, and DNA biosensor have been applied to electrochemical biosensing of aflatoxin. In this paper, the research progress of different kinds of sensors for aflatoxin analysis is reviewed. The importance of new materials and advanced technologies for immunoassay of aflatoxin is particularly highlighted. Main problems and trends in electrochemical biosensing of aflatoxin are discussed and prospected.
Contents 1 Introduction 2 Electrochemical immunosensor 2.1 Nanomaterials 2.2 Ionic liquids 2.3 Conducting polymers 2.4 Others 3 Electrochemical enzyme sensor 4 Electrochemical DNA sensor 5 Conclusion and outlook
Yang Yukun, Wang Xiaomin, Fang Guozhen, Yun Yaguang, Guo Ting, Wang Shuo. Electrochemiluminescence Analysis Based on Molecular Imprinting Technique[J]. Progress in Chemistry, 2016, 28(9): 1351-1362.
Contents 1 Introduction 2 Common ECL system and ECL mechanism 2.1 Annihilation type ECL mechanism 2.2 Co-reactant type ECL mechanism 3 Research advances of MIPs-based ECL analysis 3.1 MIPs-ECL sensor based on solid-state light-emitting electrode 3.2 MIPs-ECL sensor based on non-solid-state Light-emitting electrode 3.3 MIPs based-solid phase extraction coupled with ECL 4 Conclusion