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Progress in Chemistry 2012, Vol. Issue (10): 1915-1927 Previous Articles   Next Articles

• Review •

Fluorescent Sensor Arrays

Liu Yuan, Ding Liping*, Cao Yuan, Fang Yu   

  1. Key Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi’an 710062, China
  • Received: Revised: Online: Published:
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Sensor arrays are developed based on the knowledge of olfactory systems and have become a powerful tool in the field of molecular recognition. Sensor arrays are comprised of a series of sensor elements which generate a specific recognition pattern for each analyte. This advantage provides sensor arrays discriminatory power to identify chemically or structurally similar analytes and even complex mixed samples. Due to the high sensitivity, no need of reference systems, multiple signals, and ability to be visualized, fluorescent sensor arrays have obtained increasing attention in the field of sensor arrays. The present review introduces the advances in the fluorescent sensor arrays which can be classified into solution-based arrays, particle-based arrays and film-based arrays according to the type of the sensor elements utilized. The design strategy and sensing mechanism of fluorescent sensor arrays and their applications in the field of recognition of metal ions, organic chemicals and biomolecules are highlighted. Contents 1 Introduction
2 Solution-based fluorescent sensor arrays
2.1 Small fluorophores as sensor element
2.2 Fluorescent conjugated polymer as sensor element
3 Particle-based fluorescent sensor arrays
3.1 Imprinted fluorescent mesoporous silica as sensor element
3.2 Fluorescent gold nanoparticles as sensor element
3.3 Polyfluorophore DNA-modified PEG-PS beads as sensor element
4 Film-based fluorescent sensor arrays
4.1 Physisorbed film as sensor element
4.2 Chemically-assembled film as sensor element
5 Conclusion and outlook
Key words: fluorescence, sensor array, pattern recognition, particles, films

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Abstract

Fluorescent Sensor Arrays