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Progress in Chemistry 2000, Vol. 12 Issue (02): 203- Previous Articles   Next Articles

• Review •

Progress on CoMFA Research

Zhu Jie;Sheng Chunquan;Zhang Wannian   

  1. College of Pharmacy, Second Military Medical University, Shanghai 200433, China
  • Received: Revised: Online: Published:
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Comparative molecular field analysis (CoMFA ) is a relatively new 3D-QSAR method, which is used widely and successfully. But it has some defects in fitting rules, new fields, the selection of variables and data statistics. The recent improvements of the CoMFA method is reviewed in this paper, With these improvements, CoMFA will play a more important role in designing new drugs in future.

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Abstract

Progress on CoMFA Research