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Progress in Chemistry 1998, Vol. 10 Issue (01): 55- Previous Articles   Next Articles

• Review •

The Receptor Site ModelMethod in 3D-QSAR Research

Zhou Jiaju;Chen Hongming;Xie Guirong;Ren Tianrui;Xu Zhihong   

  1. Laboratory of Computer Chemistry, Institute of Chemical Metallurgy,Chinese Academy of Sciences, Beijing 100080, China
  • Received: Revised: Online: Published:
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The recent progress of the 3D2QSAR research and the applications of the method of receptor sitemodel in 3D2Q SAR research have been reviewed. Compass, GERM and RSM algorithms for building receptor sitemodel were introduced. Thesem ethods provide a new idea to the QSAR research under the condition that the three dimensional structure of receptor is unknown.

Key words: receptor site model, 3D2Q SAR

CLC Number: 

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