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Progress in Chemistry 2019, Vol. 31 Issue (7): 954-968 DOI: 10.7536/PC181219 Previous Articles   Next Articles

Agroactive Nucleosides from Microorganisms

Shaoyong Ke, Zhaoyuan Wu, Zhongyi Wan, Wei Fang, Yani Zhang, Kaimei Wang**()   

  1. Hubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan 430064, China
  • Received: Online: Published:
  • Contact: Kaimei Wang
  • Supported by:
    National Key R&D Program(2017YFD0201205); Hubei Provincial Fund for Innovative Science and Technology in Agriculture(2016-620-000-039)
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Microbial natural products play important roles in research and development of new agrochemicals. As a group of important physiologically active compounds, nucleosides from microorganisms have very diverse structures and bioactivities. This review summarizes the agroactive nucleosides from different microorganisms in three categories: nucleoside bases, nucleosides and derivatives, and the nucleotides. It mainly focuses on the producing microorganisms, the structural diversity, agroactivities, including the mode of actions of insecticidal, fungicidal, and antiviral activities. The authors hope that it will benefit the development of new agricultural antibiotics and new agrochemicals.

Key words: microbial nucleoside, structure diversity, insecticidal activity, fungicidal activity, herbicidal activity, antiviral activity, mode of action
Scheme. 1 Microbially agroactive nucleosides bases and their derivatives[6,7,8,9,10,11,12]
Scheme. 2 Microbially agroactive adenosines and their derivatives[14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54]
Scheme. 3 Microbially agroactive adenosines and their derivatives[55,56,57,58,59,60,61,62,63,64,65,66]
Scheme. 4 Microbially agroactive guanosine derivatives[30, 47]
Scheme. 5 Microbially agroactive cytosidines and their derivatives[68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88]
Scheme. 6 Microbially agroactive uridines and their derivatives[91,92,93,94,95,96]
Scheme. 7 Polyoxins from microorganisms[97,98,99,100,101,102,103,104]
Scheme. 8 Nikkomycins from microorganisms[106,107,108,109,110,111]
Scheme. 9 Neopolyoxins and hydrid antibiotics of polyoxins and nikkomycins from microorganisms[118,119,120,121,122]
Scheme. 10 Microbially agroactive nucleotide derivatives[127,128,129,130,131,132]
Scheme. 11 Microbially agroactive nucleosides containing pyrrolo[2,3-d]pyrimidine unit[134,135,136,137,138,139,140,141,142,143]
Scheme. 12 Microbially agroactive nucleosides containing pyrazolopyrimidine unit[144,145,146]
Scheme. 13 Other microbially agroactive nuclesides[149,150,151,152]
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Abstract

Agroactive Nucleosides from Microorganisms