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Development of Dummy Template Molecularly Imprinted Techniques in Sample Pretreatment

Xu Zhigang, Liu Zhimin, Yang Baomin, Zi Futing   

  1. Faculty of Science, Kunming University of Science and Technology, Kunming 650093, China
  • Received: Revised: Online: Published:
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Molecularly imprinted polymers are widely used in complex sample pretreatment. It could eliminate the interference of complicated matrix. It shows high selectivity to its template and good chemical stablity. A dummy template instead of a template molecule to prepare molecularly imprinted polymer could overcome the dissolvability of the template in polymerization solvent. The dummy template molecularly imprinted polymer still shows specific ability to the structure analogous analyte. It could avoid the risk of leakage of template molecule in trace analysis. In this paper, the development of dummy template molecularly imprinted techniques in sample preparation is summarized, including the application of dummy template molecularly imprinted techniques in solid phase extraction, solid phase microextraction, chromatographic solid phase material and matrix solid phase dispersion extraction. The trends of dummy template molecularly imprinted techniques in sample pretreatment are also discussed. Contents 1 Introduction
2 Molecularly imprinted sample pretreatment techniques
3 Dummy template molecularly imprinted sample pretreatment techniques
3.1 Solid phase extraction
3.2 Solid phase microextraction
3.3 Chromatographic solid phase material
3.4 Matrix solid phase dispersion extraction
3.5 Other techniques
4 Conclusions and outlook
Key words: dummy template, molecularly imprinted technique, sample pretreatment, solid phase extraction, solid phase microextraction, matrix solid phase dispersion extraction

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