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Progress in Chemistry 2011, Vol. 23 Issue (9): 1959-1972 Previous Articles   Next Articles

• Review •

A Review of Antioxidant Activity Studies Using Electron Paramagnetic Resonance Methods

Cai Yu1, Wang Yongjian2, Wang Jian1, Song Chan1, Yu Ao1*   

  1. 1. Central Laboratory, College of Chemistry, Nankai University, Tianjin 300071, China;
    2. Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, China
  • Received: Revised: Online: Published:
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Antioxidants play a vital role in many fields, such as chemical engineering, food industry and life sciences, and are attracted much attention in recent years because of their beneficial influence on human health. In this paper, the measurement principles and methods for the determination of antioxidant activity by electron paramagnetic resonance (EPR) technique are introduced briefly. Progress in the EPR studies on antioxidant activity of natural and synthetic antioxidants in the last two decades is reviewed in detail, especially on the EPR indexes which characterize the antioxidant activity quantitatively, and the EPR application on the effects (substituent effect, heteroatomic effect, and solvent effect) which influence the antioxidant activity and the antioxidant mechanism.

Contents
1 Introduction
2 Theoretical aspects of EPR
3 Indexes and their determination of antioxidant activity by EPR
3.1 Kinetic mechanism of lipid peroxidation using EPR
3.2 The determination of A—H bond dissociation enthalpies BDE(A—H)
3.3 The determination of stoichiometric coefficient n and inhibition rate constant of peroxidation kinh
4 Application of EPR spectrometer on the studies of antioxidant activity
4.1 Natural antioxidants
4.2 Artificial antioxidants
5 Conclusions and Outlook

 

Key words: electron paramagnetic resonance (EPR), electron spin resonance (ESR), antioxidant activity

CLC Number: 

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