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Progress in Chemistry 2010, Vol. 22 Issue (11): 2179-2190 Previous Articles   Next Articles

• Review •

Application of Quantum Dots Based Electrochemical Biosensors

Liu Jianyun   Huang Qianming**   Wang Xianxiang**   Li Zhen   Chen Huaping   

  1. (College of Life and Science，Sichuan Agricultural University, Ya’an 625014,China)
  • Received: Revised: Online: Published:
  • Contact: Huang Qianming E-mail:hqming@sicau.edu.cn
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Quantum dots(QDs) have attracted enormous interest due to their many novel properties such as unique optical, electrochemical and electrochemical luminescence properties. One of the most active trends is the application of QDs in electrochemical and biological sensing, due to their high surface-to-volume ratio, high reactivity and small size. Slight changes in the external environment will lead to significant changes in particle valence and electron transfer. Based on these significant changes, QDs can be used to construct electrochemical biosensor with biological macromolecules, which is characterized by high sensitivity, rapid response and high selectivity. In this article, we review their applications in electrochemical luminescence sensors, immunosensors, DNA sensors, protein sensors, pesticide sensors and carbohydrate sensors. Meanwhile, the prospects and research directions of QDs are given based on the analysis of this research field.

Contents
1 Introduction
2 Quantum dots
2.1 Optical properties of quantum dots
2.2 Electrochemical properties of quantum dots
2.3 Electrochemical luminescence properties of quantum dots
3 Applications of quantum dots based electrochemical biosensors
3.1 Applications of quantum dots based electrochemical luminescence sensors
3.2 Applications of quantum dots based electrochemical Immunosensor
3.3 Applications of quantum dots based electrochemical DNA sensors
3.4 Applications of quantum dots based electrochemical protein sensors
3.5 Applications of quantum dots based electrochemical pesticide sensors
3.6 Applications of quantum dots based electrochemical carbohydrate sensors
4 Conclusions and outlook

Key words: quantum dots (QDs), bioelectroanalysis, biosensors, electrochemical luminescence (ECL), Chemically modified electrode

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