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Progress in Chemistry 2010, Vol. 22 Issue (08): 1626-1632 Previous Articles   Next Articles

• Review •

Composites of Intelligent PNIPAM Hydrogels and Au Nanoparticles

Jiang Caiyun  Qian Weiping**   

  1. (State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096)
  • Received: Revised: Online: Published:
  • Contact: Qian Weiping E-mail:wqian@seu.edu.cn
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The composites which are made of intelligent hydrogels, ploy ( N-isopropyl acrylamide) ( PNIPAM ) and Au nanoparticles ( AuNPs ), have drawn great attentions because they have thermo-responsive behavior of PNIPAM with optical properties of AuNPs. Here, the preparation methods of the composites and their traits are reviewed, which include direct dispersion, in-situ polymerization approach, in-situ synthesis of nanoparticles, template methods, et al. Furthermore, the applications of these composites are introduced in aspects of photothermally modulated drug delivery, surface-enhanced Raman scattering, catalysis, on-off valve, sensing and supramolecular self-assembly. Finally, the current problems and the prospect of the future researches on the composites are proposed.

Contents 
1 Introduction 
2 Preparation of Au-PNIPAM 
2.1 Direct Dispersion (Mixed together) 
2.2 In-situ Polymerization 
2.3 In-situ Synthesis of  Au Nanoparticles 
2.4 Template Methods 
2.5 Other Methods 
3 Applications of Au-PNIPAM 
3.1 Photothermally modulated drug delivery
3.2 Surface-enhanced Raman Scattering 
3.3 Catalysis 
3.4 On-Off Valve 
3.5 Sensing 
3.6 Supramolecular self-assembly 
4 Conclusion

CLC Number: 

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