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Progress in Chemistry 2010, Vol. 22 Issue (01): 220-224 Previous Articles   Next Articles

• Invited Article •

3-Nitrobenzanthrone in Environment

Li Huaijian1; Li Qiang2; Wang Wu1,3**; Zhang Hongwei3; Li Li4   

  1. (1.Institute of Environmental Pollution and Health, Shanghai University, Shanghai 200444, China; 2. School of Stomatology, Tongji University, Shanghai 200072, China; 3. Southern Medical University, Guangzhou 510515, China; 4. College of Resources and Environment, Sichuan Agricultural University, Ya'an 625014, China)
  • Received: Revised: Online: Published:
  • Contact: Wang Wu E-mail:wangwu@shu.edu.cn
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3-Nitrobenzanthrone is a widespread environmental pollutant and suspected to be carcinogenic for human beings. It is detectable in different environmental media, for example, surface soil, rainwater, airborne particulate matter, etc. Because its concentration is the highest in diesel exhaust, the dominant sources of 3-nitrobenzanthrone are probably unidentified combustion process. The mutagenicity and genotoxicity of 3-nitrobenzanthrone by biological assays both in vivo and in vitro are very high, comparable to 1,8-dinitropyrene, which is the direct mutagen of strongest activity so far reported in the literature. Therefore, 3-nitrobenzanthrone has become one of the highlights in the fields of environmental chemistry and toxicology. This paper summaries the present studies on 3-nitrobenzanthrone, including the sources, analytical techniques, mutation mechanisms, environmental effects, and so on. The future research directions have also been prospected.

Contents
1 Introduction
2 The sources of 3-nitrobenzanthrone
3 Analytical methods of 3-nitrobenzanthrone
4 The mechanism of 3-nitrobenzanthrone induced mutagenesis
5 Prospective

Key words: 3-nitrobenzanthrone, environmental pollutants, mutagenicity, genotoxicity

CLC Number: 

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Abstract

3-Nitrobenzanthrone in Environment