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Progress in Chemistry 2010, Vol. 22 Issue (01): 186-193 Previous Articles   Next Articles

• Invited Article •

MRI Contrast Agent for the Diagnosis of Tumor

Wang Lingyun;  Chen Qiuyun**;  Wei Bin   

  1. (College of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang 212013, China)
  • Received: Revised: Online: Published:
  • Contact: Chen Qiuyun E-mail:chenqy@ujs.edu.cn
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Magnetic resonance imaging is commonly used as clinical non-invasive means in early diagnosis of tumor. It often requires contrast agent to improve the effectiveness of diagnosis. MRI contrast agent can shorten proton relaxation time and change the signal intensity of proton indirectly. It also can change the relaxation rate of the water proton in the sub-regional organizations of the body and improve the imaging contrast between normal and abnormal tissues. In this paper, the research progress of contrast agent was systematically reviewed. The development of paramagnetic contrast agents was discussed.

Contents
1 Introduction
2 The research about MRI contrast agent for cancer detection
2.1 Small molecule paramagnetic contrast agent
2.2 Macromolecular paramagnetic contrast agent
2.3 SPIO particles and ferromagnetic particles
2.4 Nano-structure contrast agent
3 Prospects

Key words: magnetic resonance imaging, contrast agents, tumor

CLC Number: 

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