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Progress in Chemistry 2009, Vol. 21 Issue (6): 1356-1363 Previous Articles   Next Articles

• Review •

Hydroxyl in Biological Apatite and Its Crystal Structure

Shen Juan|Zuo Yi| Wang Xuejiang; |Zhang Li; |Li Yan; |Li Yubao**   

  1. (The Research Center for Nano-Biomaterials, Analytical and Testing Center, Sichuan University, Chengdu 610064, China)
  • Received: Revised: Online: Published:
  • Contact: Li Yubao E-mail:nic7504@scu.edu.cn
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The chemical composition, crystal structure, and short-range order of apatite crystals of bone play an essential role in the biological and structural functions of bone substance. However, the question of whether the apatite crystals of bone contain hydroxyl ion remains, and the crystal structure of carbonated apatite still remains subject to uncertainties since the exact location of carbonate ions has not yet been determined. This review aims at highlighting on current developments in biological apatite mineral components and its crystal structure. It introduces near-absence of OH－ in bone apatite has been established through extensive study by chemical analyses and spectroscopy techniques. And carbonate ions replace both the A-site and B-site in the hydroxylapatite structure. It is anticipated to provide a deeper understanding about stability, mechanisms of substitution and many surface phenomena of biological apatite.

Contents
1 Introduction
2 Techniques in hydroxyl ion study on biological and synthetic apatite
2.1 NMR study on hydroxyl ion in apatite
2.2 FT-IR and Raman spectroscopy study on hydroxyl ion in apatite
2.3 INS study on hydroxyl ion in apatite
3 Crystal structure of biological and synthetic apatite
3.1 Type A carbonate substitution
3.2 Type B carbonate substitution
4 Conclusions

Key words: apatite structures, bones, hydroxyl group, carbonate apatite, substitution

CLC Number: 

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