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Progress in Chemistry 2009, Vol. 21 Issue (6): 1304-1311 Previous Articles   Next Articles

• Review •

Preparation and Characterization of Polymers Containing Cholic Acid Moiety

Hu Xiangzheng1**; |Liu Anjun2   

  1. （1. College of Science, Tianjin University of Science and Technology, Tianjin 300457, China； 2. College of Food Engineering and Biotechnology|Tianjin University of Science and Technology, Tianjin 300457, China）
  • Received: Revised: Online: Published:
  • Contact: Hu Xiangzheng E-mail:hxz0903@yahoo.com.cn
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Cholic acid is a natural compound that is synthesized in the animal body, which has special chemical structure and good biocompatibility. Polymers prepared from cholic acid can preserve some properties of cholic acid, such as facial amphiphilicity, chirality, reactivity of the side groups and capacity of self-assembling. In chemical and pharmaceutical fields, polymeric materials containing cholic acid can be used widely. This paper reviews the preparation and characterization of polymers containing cholic acid obtained by free radical polymerization, polymers modified with cholic acid and polycondensation of cholic acid, etc. The development of polymers containing cholic acid in the future is also forecasted.

Contents
1 Introduction
2 Polymeric materials containing cholic acid obtained by radical polymerization
2.1 Polymers obtained from polymerization of vinylic group at position C3
2.2 Polymers obtained from polymerization of vinylic group at position C24
2.3 Polymers obtained from polymerization of vinylic groups at positions C3,C7 and C12
3 Polymers obtained from chemical modify with cholic acid
3.1 Polymers with cholic acid moieties as side group
3.2 Polymers end-capped with cholic acid
4 Polycondensation of cholic acid
5 Molecular umbrellas
6 Dendritic polymer
7 Applications of cholic acid on other fields
8 Conclusions

Key words: cholic acid, polymer material, preparation, characterization

CLC Number: 

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