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Progress in Chemistry 2009, Vol. 21 Issue (12): 2696-2703 Previous Articles   Next Articles

• Review •

The Research of Modified Poly(para-dixoane)

Bai Wei;  Chen Dongliang;  Li Qing;  Zhang Zhiping;  Xiong Chengdong**   

  1. （Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, China)
  • Received: Revised: Online: Published:
  • Contact: Xiong Chengdong E-mail:xcd1633@yahoo.com.cn
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Poly(para-dioxanone) (PPDO) is used as a biomaterial for tissue engineering, bone fracture fixation and controlled drug delivery due to its excellent biodegrability, bioabsorbability, biocompatibility and good flexibility. Furthermore, PPDO presents outstanding potential for general medical devices such as films, molded products, laminates, foams, non-woven materials, adhesives, and coatings. However, its polymerization method and structure, etc have hindered development of commercial applications. The recent progress in modifiration of poly(para-dixanone) is reviewed in this paper, which includes blending modification of PPDO, chemical modification of PPDO and filling modification of PPDO. Blending with other polymers is a simple and convenient way of modifying the crystalline and degradation properties of PPDO. Chemical modification is one way of improveing the properties of poly(para-dixanone), such as its solubility, molecular weight, thermal stability and so on. Filling modification of PPDO can implement each other's complement of their advantage, these novel properties will develop its wide application.

Contents
1 Introduction
2 Modification methods of PPDO
2.1 Blending Modification of PPDO
2.2 Chemical Modification of PPDO
2.3 Filling Modification of PPDO
3 Conclusions and Outlook

Key words: poly(para-dioxanone), modification, biodegradation polymers

CLC Number: 

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