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Progress in Chemistry 2009, Vol. 21 Issue (10): 2176-2182 Previous Articles   Next Articles

• Review •

Phosphorylcholine Modified Polymers

Meng Sheng;  Zhou Huan;  Zhong Wei**;  Du Qiangguo   

  1. (The Key Laboratory of Molecular Engineering of Polymers, Ministry of Education, Department of Macromolecular Science, Fudan University, Shanghai 200433, China)
  • Received: Revised: Online: Published:
  • Contact: Zhong Wei E-mail:weizhong@fudan.edu.cn
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The synthesis of the “bioinspired” polymers with phospholipids-like structures has been developed as an important field in improving the biocompatibilities of biomedical materials. In the present article, the syntheses of phosphorylcholine-contained polymers as well as the phosphorylcholine-modification methods of several systems are summarized. Furthermore, the applications of phosphorylcholine-modified polymers in biomedical fields, such as tissue engineering, blood purification, drug delivery and biosensors are briefly reviewed. Also, the development and applications of the phosphorylcholine-modified polymers in the future are discussed.

Contents
1 Phosphorylcholine-containing monomers and their copolymers
2 Grafting modification of phosphorylcholine on material surfaces
3 Phosphorylcholine modification in biodegradable systems
4 Application and prospects of Phosphorylcholine-containing polymers

Key words: phosphorylcholine, phospholipid polymers, modification, biomedical materials

CLC Number: 

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Abstract

Phosphorylcholine Modified Polymers