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Progress in Chemistry 2009, Vol. 21 Issue (01): 210-216 Previous Articles   Next Articles

• Review •

Nanomaterials Based Electrochemical Biosensors

Yang Haipeng**;Chen Shiguo;Li Chunhui;Chen Dongcheng;Ge Zaochuan   

  1. (Shenzhen Key Laboratory of Special Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China)
  • Received: Revised: Online: Published:
  • Contact: Yang Haipeng E-mail:yanghp@szu.edu.cn
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Biosensors which utilize immobilized bioactive compounds(such as enzymes, antigen, antibody, DNA, etc.) for the conversion of the target analytes into electrochemically detectable products is one of the most widely used detection methods and has become an area of wide ranging research activity. The advances in biocompatible nano technology make it possible to develop new biosensors. A variety of biosensors with high sensitivity and excellent reproducibility based on nano technology have been reported in recent years. In this paper, the development of the researches on nano amperometric biosensors, one of the most important branches of biosensors, is reviewed. Nanoscale architectures here involve nano-particles, nano-wires and nano-rods, nano-sheet, nano-array, and carbon nanotube, etc. Remarkable sensitivity and stability have been achieved by coupling immobilized bioactive compounds and these nanomaterials.

Contents
1 Introduction to biosensors
2 Nanomaterials based electrochemical biosensors
2.1 Challenges and developments of biosensors
2.2 Introduction of nanomaterials
2.3 Nanomaterials based electrochemical biosensors
2.3.1 Nano particles based electrochemical biosensors
2.3.2 Nanowires and nanorods based electrochemical biosensors
2.3.3 Carbon nanomaterials based electrochemical biosensors
2.3.4 Nano array based electrochemical biosensors
2.3.5 Nanosheets based electrochemical biosensors
3 Concluding remarks

CLC Number: 

[ 1 ]  董绍俊(Dong SJ ) , 车广礼(Che GL) , 谢远武(Xie YW) . 化学修饰电极( 修订版) ( Chemical Modified Electrode , Revised Edition) , 北京: 科学出版社(Beijing : Science Press) , 2003 ,501 —538
[ 2 ]  池其金(Chi Q J ) , 董绍俊(Dong S J ) . 分析化学(Chinese Journal of Analytical Chemistry) , 1994 , 22 : 1065 —1072
[ 3 ]  何星月(He X Y) , 刘之景(Liu Z J ) . 物理( Physics) , 2003 ,32 : 249 —252
[ 4 ]  陈旭(Chen X) . 中国科学院长春应用化学研究所博士学位论文( Doctoral Dissertation of Changchun Institute of Applied Chemistry , Chinese Academy of Sciences) , 2002
[ 5 ]  王丽红(Wang L H) , 张林(Zhang L) , 陈欢林(Chen HL) . 化学进展(Progress in Chemistry) , 2006 , 18 : 440 —452
[ 6 ]  张炯(Zhang J ) , 万莹(Wan Y) , 王丽华(Wang L H) 等. 化学进展(Progress in Chemistry) , 2007 , 19 : 1576 —1584
[ 7 ]  金利通(Jin L T) , 鲜跃仲(Xian Y Z) , 张芬芬(Zhang F F) .华东师范大学学报(自然科学版) (Journal of East China Normal University(Natural Science) ) , 2005 , 5P6 : 13 —24
[ 8 ]  吴子刚(Wu Z G) , 林鸿波(Lin H B) , 封伟(Feng W) . 化学进展(Progress in Chemistry) , 2006 , 18 : 1200 —1207
[ 9 ]  Davis J , Vaughan D H , Cardosi M F. Enzyme Microb. Tech. ,1995 , 17 : 1030 —1035
[10 ]  Tess M E , Cox J A. J . Pharm. Biomed. Anal . , 1999 , 19 : 55 —68
[11 ]  Li J , Tan S N , Ge H. Anal . Chim. Acta , 1996 , 335 : 137 —145
[12 ]  缪煜清(Liao YQ) , 刘仲明(Liu ZM) , 官建国(Guan J G) . 传感器技术(Journal of Transducer Technology) , 2002 , 21 : 61 —64
[13 ]  唐芳琼(Tang F Q) , 孟宪伟(Meng X W) , 陈东(Chen D) 等.中国科学B (Science in China B) , 2000 , 30 : 119 —124
[14 ]  张玲(Zhang L) . 中国科学技术大学博士学位论文(Doctoral Dissertation of The University of Science and Technology of China) ,2007
[15 ]  麦智彬(Mai Z B) , 谭学才(Tan X C) , 邹小勇(Zou X Y) . 分析测试学报( Journal of Instrumental Analysis ) , 2006 , 25 :120 —125
[16 ]  Zeng YL , Huang Y F , Shen GL , et al . Electrochem. Commun. ,2007 , 185 —190
[17 ]  Manesh KM, Kim H T, Santhosh P , et al . Biosens. Bioelectron. ,2008 , 23 : 771 —779
[18 ]  Chandrashekar T K, Willgen H V , Ebersole M H. J . Phys. Chem. ,1984 , 19 : 4326 —4332
[19 ]  Zhao J , Henkens R W, Stonehuerner J , et al . J . Electroanal .Chem. , 1992 , 327 : 109 —119
[20 ]  刘志贤(Liu Z X) , 陈钢进(Chen GJ ) , 周永洽(Zhou YQ) 等.化学试剂(Chemical Reagents) , 1996 , 18 : 260 —262
[21 ]  Xiao Y, Ju H , Chen H. Anal . Chim. Acta , 1999 , 391 : 73 —77
[22 ]  Jia J , Wang B , Wu A , et al . Anal . Chem. , 2002 , 74 : 2217 —2223
[23 ]  Chen Z, Ou X, Tang F , et al . Colloid Surface B , 1996 , 7 : 173 —179
[24 ]  Li Q W, Luo GA , Feng J , et al . Electroanal . , 2001 , 13 : 413 —416
[25 ]  Qhobosheane M, Santra S , Zhang P , et al . Analyst , 2001 , 126 :1274 —1278
[26 ]  Hilliard L , Zhao X, Tan W. Anal . Chim. Acta , 2002 , 470 : 51 —56
[27 ]  Luo X, Xu J , Chen H , et al . Sensor Actuat . B , 2004 , 97 : 249 —255
[28 ]  Zhang F F , Wan Q , Jin L T, et al . J . Electroanal . Chem. , 2004 ,571 : 133 —138
[29 ]  Jena B K, Raj C R. Anal . Chem. , 2006 , 78 : 6332 —6339
[30 ]  Neufeld T, Biran D , Popovtzer R , et al . Anal . Chem. 2006 , 78 :4952 —4956
[31 ]  侯宪全(Hou XQ) , 任湘菱(Ren XL) , 唐芳琼(Tang F Q) 等.分析化学(Chinese Journal of Analytical Chemistry) , 2006 , 34 :303 —306
[32 ]  Zhao Z X, Qiao M Q , Yin F , et al . Biosens. Bioelectron. , 2007 ,22 : 3021 —3027
[33 ]  Jena B K, Raj C R. Electroanal . , 2007 , 19 : 816 —822
[34 ]  Huang Y X, Zhang W J , Xiao H , et al . Biosens. Bioelectron. ,2005 , 21 : 817 —821
[35 ]  Bai Y, Yang H , Yang W W, et al . Sensor Actuat . B : Chem. ,2007 , 124 : 179 —186
[36 ]  Chandra D , Jena B K, Raj C R , et al . Chem. Mater. , 2007 , 19 :6290 —6296
[37 ]  Yang H P , Zhu Y F. Anal . Chim. Acta , 2005 , 554 : 92 —97
[38 ]  Yang H P , Zhu Y F. Talanta , 2006 , 68 : 569 —574
[39 ]  Yang H P , Zhu YF. Biosens. Bioelectron. , 2007 , 22 : 2989 —2993
[40 ]  谢海燕(Xie H Y) , 陈薛钗(Chen X C) , 邓玉林(Deng YL) .化学进展(Progress in Chemistry) , 2007 , 19 : 1026 —1033
[41 ]  郑静(Zheng J ) , 何品刚(He P G) , 方禹之(Fang Y Z) 等. 中国科学B (Science in China B) , 2006 , 36 : 485 —492
[42 ]  Liu Q , Lu X B , Li J , et al . Biosens. Bioelectron. , 2007 , 22 :3203 —3209
[43 ]  Jie G F , Zhu J J , Chen H Y, et al . Anal . Chem. , 2007 , 79 :5574 —5581
[44 ]  Jie G F , Zhang J J , Zhu J J , et al . Anal . Chem. , 2008 , 80 :4033 —4039
[45 ]  Varshney M, Li Y B. Biosens. Bioelectron. , 2007 , 22 : 2408 —2414
[46 ]  Lu Y C , Chuang Y S , Yew T R , et al . Biosens. Bioelectron. ,2008 , 23 : 1856 —1861
[47 ]  Liu B , Zeng H C. J . Am. Chem. Soc. , 2003 , 125 : 4430 —4431
[48 ]  Zhang F F , Wang X L , Jin L T. Anal . Chim. Acta , 2004 , 519 :155 —160
[49 ]  Willner I , Heleg-Shabtai V , Blonder R , et al . J . Am. Chem.Soc. , 1996 , 118 : 10321 —10322
[50 ]  Rakitin A , Aich P , Papadopoulos C , et al . Phys. Rev. Lett . ,2001 , 86 : 3459 —3694
[51 ]  Yi C , Wei Q Q , Park H K, et al . Science , 2001 , 293 : 1289 —1292
[52 ]  Curreli M, Li C , Sun Y H , et al . J . Am. Chem. Soc. , 2005 ,127 : 6922 —6923
[53 ]  HahmJ I , Lieber C M. Nano Lett . , 2004 , 4 : 51 —54
[54 ]  Hrapovic S , Luong J H T. Anal . Chem. , 2003 , 75 : 3308 —3315
[55 ]  Kawashima T, Mizutani T, Nakagawa T, et al . Nano Lett . , 2008 ,8 : 362 —368
[56 ]  Yun Y H , Dong Z Y, Shanov V , et al . Nano Today , 2007 , 2 : 30 —37
[57 ]  Wang J , Musameh M, Lin Y H. J . Am. Chem. Soc. , 2003 , 125 :2408 —2409
[58 ]  Hrapovic S , Liu YL , Male KB , et al . Anal . Chem. , 2004 , 76 :1083 —1088
[59 ]  Zhang M G, Smith A , Gorski W. Anal . Chem. , 2004 , 76 : 5045 —5050
[60 ]  Liu Y, Wang M K, Dong S J , et al . Biosens. Bioelectron. , 2005 ,21 : 984 —988
[61 ]  张凌燕(Zhang L Y) , 袁若(Yuan R) , 柴雅琴(Chai Y Q) 等. 化学学报(Acta Chimica Sinica) , 2006 , 64 : 1711 —1715
[62 ]  段大雪(Duan D X) , 楚霞(Chu X) . 化学传感器(Chemical Sensors) , 2006 , 26 : 29 —33
[63 ]  Zeng Y L , Shen G L , Yu R Q , et al . Electrochem. Commun. ,2007 , 9 : 185 —190
[64 ]  Yang M H , Shen G L , Yu R Q , et al . Biosens. Bioelectron. ,2006 , 21 : 1791 —1797
[65 ]  Manesh KM, Kim H T, Santhosh P , et al . Biosens. Bioelectron. ,2008 , 23 : 771 —779
[66 ]  Huang J S , Hou H Q , You T Y, et al . Adv. Funct . Mater. , 2008 ,18 : 441 —448
[67 ]  Miao Y, Yuan C. Anal . Lett . , 1999 , 32 : 1287 —1290
[68 ]  Yang M H , He Y, Shen GL. Biomaterials , 2006 , 27 : 5944 —5950
[69 ]  Chang H X, Yuan Y, Guan Y F , et al . Anal . Chem. , 2007 , 79 :5111 —5115
[70 ]  Tu Y, Huang Z P , Wang D Z, et al . Appl . Phys. Lett . , 2002 , 80 :4018 —4020
[71 ]  Tu Y, Lin Y, Ren Z F. Nano Lett . , 2003 , 3 : 107 —109
[72 ]  Lin Y, Lu F , Tu Y, et al . Nano Lett . , 2004 , 4 : 191 —195
[73 ]  Liu A , Wei M, Zhou H. Anal . Chem. , 2005 , 77 : 8068 —8074
[74 ]  Mousty C , Cosnier S. J . Appl . Clay Sci . , 2004 , 27 : 159 —177
[75 ]  Shan D , Mousty C , Cosnier S. Anal . Chem. , 2004 , 76 : 178 —183
[76 ]  Zhang L , Zhang Q , Li J H , et al . Biosens. Bioelectron. , 2007 ,23 : 102 —106
[77 ]  Xiao H , Wu J L , Yang WS , et al . Chinese Sci . Bull . , 2008 , 53 :1152 —1156

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