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Progress in Chemistry 2009, Vol. 21 Issue (01): 134-142 Previous Articles   Next Articles

• Review •

Bio-Detection, Cellular Imaging and Cancer Photothermal Therapy Based on Gold Nanorods

Ma Zhanfang**;Tian Le;Di Jing;Ding Teng   

  1. (Department of Chemistry, Capital Normal University, Beijing 100037, China)
  • Received: Revised: Online: Published:
  • Contact: Ma Zhanfang E-mail:mazhanfang@yahoo.com
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Due to unique and tunable surface plsmon resonance properties, gold nanorods have widely potential and important applications, i.e., fabrications of nanoconposites, nanodevices, nanobiotechnology, and biomedicine. Gold nanorods, therefore, have been attracted much attention. The latest advances on the applications of gold nanorods involving biological detection, cellular imaging, and cancer photothermal therapy are reviewed in this paper. Meanwhile the optical properties and several main approaches of surface modification of gold nanorods are also introduced. In addition the main issues existing in the biological applications are discussed.

Contents
1 Optical properties of gold nanorods
2 Surface modifications of gold nanorods
2.1 Silica-coated gold nanorods
2.2 Modification of gold nanorods using biomolecules
3. Applications of gold nanorods in biodetection, bioimaging, and cancer photothermal therapy
3.1 Applications of gold nanorods in bio-molecular detection
3.2 Applications of gold nanorods in cell imaging and cancer photothermal therapy
4 Conclusion and outlook

Key words: gold nanorods, molecular detection, cellular imaging, photothermal therapy

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