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Progress in Chemistry 2008, Vol. 20 Issue (0708): 1151-1157 Previous Articles   Next Articles

• Review •

Synthesis and Applications of 2-Methacryloyloxyethyl Phosphorylcholine Monomer and Its Polymers

Ma Jiani; Gong Ming; Zhang Shiping; Gong Yongkuan**   

  1. (Department of Chemistry and Institute of Material Science & New Technology, Northwest University, Xi’an 710069, China)
  • Received: Revised: Online: Published:
  • Contact: Gong Yongkuan
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The research on 2-methacryloyloxyethyl phosphorylcholine(MPC) and its polymers by mimicking the structure of outer cell membrane has been a new hot topic. Numerous studies have demonstrated that the surface of materials modified with MPC polymers shows excellent hemocompatibility and tissue compatibility. In this article, the synthesis of MPC monomer and its polymers is reviewed. The applications of MPC polymers in biomedical fields, such as artificial organs, tissue engineering, blood purificaion, controlled drug delivery and gene therepy, are summerized briefly. Furthermore, the prospects of research and application of MPC polymers are also discussed.
Key words: biomaterials, biocompability, phosphorylcholine, MPC, phospholipid polymer

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