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Progress in Chemistry 2008, Vol. 20 Issue (06): 984-988 Previous Articles   Next Articles

• Review •

Scanning Near-field Optical Microscope and Its Applications in the Field of Single Molecules Detection

Hu Mingqian; Cai Jiye**

  

  1. (Department of Chemistry,College of Life Science and Technology,Jinan University,Guangzhou 510632,China)
  • Received: Revised: Online: Published:
  • Contact: Cai Jiye
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Scanning near-field optical microscope (SNOM) has a unique properties in the field of optical microscope. It breaks through optical diffraction limit, having single molecules detection(SMD) sensitivity without injurying biological samples. This article describes the basic principles of SNOM. Recent advances of SNOM in SMD and applications of SNOM combined with quantum dots(QDs) are introduced. The future prospectives of SMD are also presented.

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