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Progress in Chemistry 2008, Vol. 20 Issue (05): 740-746 Previous Articles   Next Articles

• Review •

Polymer Nanoparticles for the Delivery of Drug and Gene

Zhang Yue1; Yu Ao2; Wang Yongjian1**   

  1. (1. Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science, Nankai University, Tianjin 300071, China; 2. Central Laboratory, Nankai University, Tianjin 300071, China)
  • Received: Revised: Online: Published:
  • Contact: Wang Yongjian
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Polymer nanoparticles are used as carriers for the delivery of drug and gene. It has been one of the most attractive areas because of its scientific value and full potential of application. In this paper, an overview of polymer nanoparticles for the delivery of drug and gene is presented with a focus on typical examples, such as macromolecular drugs, polymer–drug and polymer–protein conjugates, polymeric micelles containing covalently bound drug, and polymer–DNA delivery. The existing problems and future development are also discussed.
Key words: polymers, drug delivery, cancer therapeutics, gene therapeutics

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