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Progress in Chemistry 2008, Vol. 20 Issue (01): 1-5   Next Articles

• Invited Article •

Click Chemistry - Definition and Aims

M.G.Finn; Hartmuth C. Kolb; Valery V. Fokin; K.Barry Sharpless(author); Zhang Xinhao; Wu Yundong(translator)*

  

  1. (Department of Chemistry and The Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037)
  • Received: Revised: Online: Published:
  • Contact: Wu Yundong
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[ 1 ] Bohacek R S , McMartin C , Guida W C. Med. Res. Rev. ,1996 , 16 : 3 —50
[ 2 ] Kolb H C , Finn M G, Sharpless KB. Angew. Chem. Int . Ed. ,2001 ,40 : 2004 —2021
[ 3 ] Michael A. J . Prakt . Chem. , 1893 , 48 : 94
[ 4 ] Huisgen R. In 1 ,32Dipolar Cycloaddition Chemistry (ed. Padwa A) . New York : Wiley , 1984. vol . 1 : 1 —176
[ 5 ] Torn?e C W, Christensen C , Meldal M. J . Org. Chem. , 2002 ,67 : 3057 —3062
[ 6 ] Rostovtsev V V , Green L G, Fokin V V , Sharpless KB. Angew.Chem. Int . Ed. , 2002 , 41 : 2596 —2599
[ 7 ] Lewis W G, Green L G, Grynszpan F , Radic Z , Carlier P R ,Taylor P , Finn M G, Sharpless KB. Angew. Chem. Int . Ed. ,2002 , 41 : 1053 —1057
[ 8 ] Sharpless K B. Expert Opinion on Drug Discovery , 2006 , 1 :525 —538 ; and references therein
[ 9 ] Kolb H C , Sharpless K B. Drug Discovery Today , 2003 , 8 :1128 —1137
[10] 2001 年以来关于点击化学的文献,见< http ://www.scripps.edu/chem/sharpless/click.html > . 截至2007 年7 月,这一数字已超过900 , 其中铜催化三唑成环的反应占了近90%
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Abstract

Click Chemistry - Definition and Aims