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Progress in Chemistry 2007, Vol. 19 Issue (05): 751-761 Previous Articles   Next Articles

• Review •

Synthesis of 3-Substituted Indole Derivatives

Li Jitai**;Dai Hongguang;Lin Zhiping   

  1. Key Laboratory of Analytical Science and Technology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China
  • Received: Revised: Online: Published:
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The research of indoles has been one of the most active areas of heterocyclic chemistry. In particular, 3-substitued indole derivatives have been received much attention as building blocks for the synthesis of many natural products and other biologically active compounds. Recently, there are a lot of reports on the synthesis of 3-substitued indoles from indole. In this article, The one-pot synthesis of 3-substitued indole derivatives from indoles, such as bis (indolyl) methane, β-indolylketone, β-indolylalcohol, β-indolylnitro-compound, α-indolylmethylamine is reviewed according to the kinds of catalysts.
Key words: indole, 3-substitutedindole, synthesis

CLC Number: 

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