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Progress in Chemistry 2007, Vol. 19 Issue (0203): 404-407 Previous Articles   Next Articles

• Review •

Capillary Electrophoresis and the Detection of the Abnormal Prion Protein

Zheng Yanpeng1** ;Yan Luting1;Hong Tao1,2   

  1. 1. School of Science, Beijing Jiaotong University, Beijing 100044, China
    2. Institute for Viral Disease Control and Prevention, China CDC, Beijing 100052, China
  • Received: Revised: Online: Published:
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Development and applications for capillary electrophoresis（CE） are introduced. The detection of abnormal prion protein (PrPSc) with capillary electrophoresis is discussed in detail. CE was seen as a fast developed area of analytical chemistry research in the late 1990s and use of CE to detect PrPSc in transmissible spongiform encephalopathies (TSEs) is an attractive alternative, which has been explored comparatively little.
Key words: capillary electrophoresis(CE), transmissible spongiform encephalopathies (TSEs), prion protein(PrPSc)

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