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Progress in Chemistry 2007, Vol. 19 Issue (01): 130-135 Previous Articles   Next Articles

• Review •

Analysis Techniques of Glycoprotein Glycan Structure for the Glycomics Study

Sun Xing-Quan;LI Jing;GENG Mei-Yu**;GUAN Hua-Shi   

  1. Institute of Marine Drug and Food, Ocean University of China， Qinddao 266003, China
  • Received: Revised: Online: Published:
  • Contact: Geng Meiyu
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Genetic information is transferred from DNA to protein and the protein is glycosylated subsequently, which result in the forming of glycoprotein. Comparing with DNA and protein, glycoprotein glycan possess more diverse structure and more complex functions which make the glycan play important regulational roles in many significant physiological and pathological events. And the complex function of glycan attribute to its diverse structure which is one of the important content of glycomics. The research progress in analysis techniques and methods of extract and isolate glycoprotein from sample, release the glycan and identify its structure in recent years are introduced.
Key words: glycomics, system biology, glycoprotein, glycan, isolation and purification, structure study

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