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Progress in Chemistry 2006, Vol. 18 Issue (10): 1391-1396 Previous Articles   

• Special issues •

Polymerization of CDI-Activated Charged Acidic and Basic Amino Acids Efficiently Enhanced by Na+ and Cl-

Kongjiang Wang*;Liang Xin;Jie Ren   

  1. Protein & Peptide Pharmaceutical Laboratory, Institute of Biophysics, Chinese Academy of Sciences,Beijing 100101, China
  • Received: Revised: Online: Published:
  • Contact: Kongjiang Wang
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The aqueous solution of Na+（K+）and Cl- is the reaction system for all the biological reactions. In spite of this , many ion-specific phenomena in H2O were largely considered mystery because of the limited understanding of the weak electrostatic interactions between the ions , ion and water , ion and biomolecules. Combined with the enhanced polymerization of the charged amino acids by opposite-charged common ions Na+(K+ ) and Cl- found recently by us , this paper intends to emphasize the importance of the weak electrostatic interactions of the ions with the charged peptides (proteins) in determining their structures and reactions. Its potentials in both the origins of life and in the living systems were also discussed.
Key words: aqueous solutions, Na+, K+, Cl-, enhanced polymerization, electrostatic interactions, weak interactions, peptides

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[ 1 ] Frausto da Silva J J R , Williams R J P. The Biological Chemistry of the Elements : the Inorganic Chemistry of Life , 2nd ed. Oxford University Press , 2001. 231
[ 2 ] Moyer B A , Bonneson P V. Supremolecular Chemistry of Anions (eds. Bianchi A , Bowman-James K, Garcia Espana E) . New York : Wiley-VCH , 1997. 1 —41
[ 3 ] Beer P D , Gale P A. Angew Chem. Int . Ed. Engl . , 2001 , 40 :486 —516
[ 4 ] Vilar R. Angew Chem. Int . Ed. Engl . , 2003 , 42 : 1460 —1477
[ 5 ] Diebler H , Eigen M, Igenfutz G, Mass G, Winkler R. Pure Appl . Chem. , 1969 , 20 : 93 —115
[ 6 ] Marcus J . J . Chem. Soc. Faraday Trans. , 1987 , 83 : 339 —349
[ 7 ] Kaim W, Schwederski B. Bioinorgainc Chemistry : Inorganic Chemistry of Life , 2nd ed. John Wiley &Sons , 1994. 267 —285
[ 8 ] Lippard S J . Science , 1993 , 261 : 699 —700
[ 9 ] Lohrmann R , Orgel L E. Nature , 1973 , 244 : 418 —420
[10] Beck M T. Metal Ions in Biol . Systems (ed. Sigel H) , Vol . 7.New York : Academic Press , 1978. 1 —28
[11] Ochiai E I. Cosmochemistry and the Origin of Life ( ed.Ponnamperuma C) . Dordrent :Reidel Publishing , 1981. 235 —276
[12] Ferris J P. Orig. Life Evol . Biosph. , 1993 , 23 : 307 —311
[13] Orgel L E. Orig. Life Evol . Biosph. , 1998 , 28 : 227 —234
[14] Ferris J P , Ertem G. Science , 1992 , 257 : 1387 —1389
[15] Liu R , Orgel L E. Orig. Life. Evol . Biosph. , 1998 , 28 : 47 —60
[16] Liu R , Orgel L E. Orig. Life Evol . Biosph. , 1998 , 28 : 245 —257
[17] Hill A R , Orgel L E. Orig. Life Evol . Biosph. , 1996 , 26 :539 —545
[18] Wang K J , Yao N , Li C. Orig. Life Evol . Biosph. , 2005 , 35 :313 —322
[19] Yan Q , Liu Y N , Wang K J . 14th International Conference on the Origins of Life. Beijing , 2005. 161 —162
[20] Xin L , Ma Y L , Liu Y N , Yan Q , Wang K J . Biopolymers ,2006 , 81 : 1 —7
[21] Ferris J P , Hill A R , Liu R , Orgel L E. Nature , 1996 , 381 :59 —60
[22] Wang K J , Lai P , Li S. Anal . Biochem. , 2004 , 332 : 199 —201
[23] Szostak J W, Ellington A D. The RNA World (eds. Gesteland R F , Atkins J F) . New York : Cold Spring Harbor Lab. Press ,1993. 511 —533
[24] Collins K D. Biophys J . , 1995 , 72 : 65 —76
[25] Parsegian V A. Nature , 1995 , 378 : 335 —336
[26] Vlachy V , Hribar-Lee B , Kalyuzhnyi Y V , Dill K A. Curr.Opin. Colloid Interface Sci . , 2004 , 9 :128 —132
[27] Kunz W, Nostro P L , Ninham B W. Curr. Opin. Colloid Interface Sci . , 2004 , 9 : 1 —18
[28] Omta A W, Kropman M F , Woutersen S , Bakker H J . Science ,2003 , 301 : 347 —349
[29] Bachelor J D , Olteanu A , Tripathy A , Pielak G T. J . Am.Chem. Soc. , 2004 , 126 : 1958 —1961
[30] Bostrom M, Williams D R M, Ninham B W. Phys. Rev. Lett . ,2001 , 87 , art . no. 168103
[31] Gurau M C , Lim S M, Castellana E T. J . Am. Chem. Soc. ,2004 , 126 : 10522 —10523
[32] Craig V S J , Ninham B W, Pashley R M. Nature , 1994 , 363 :317 —319
[33] Maeda H , Hiramatsu T , Ikea S. Bull . Chem. Soc. Jpn. , 1986 ,59 : 587 —591
[34] Kuntz I D , Chen K, Sharp K A , Kollman P A. Proc. Natl .Acad. Sci . , 1999 , 96 : 9997 —10002
[35] Kumpf R A , Dougherty D A. Science , 1993 , 261 : 1708 —1710
[36] Muller-Dethlefs K, Hobza P. Chem. Rev. , 2000 , 100 : 143 —167
[37] Schneider H J , Schiestel T , Zimmermann P. J . Am. Chem.Soc. , 1992 , 114 : 7698 —7703
[38] Reinhoudt D N , Crego-Calama M. Science , 2002 , 295 : 2403 —2407
[39] Morisaki N , Inoue K, Kabayashi H , et al . Tetrahedron , 1996 ,52 : 9017 —9024
[40] Arkawa T , Togunaga M. Protein & Peptide Letters , 2004 , 11 :125 —132
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