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Progress in Chemistry 2006, Vol. 18 Issue (06): 801-807 Previous Articles   Next Articles

• Review •

Recognition of Aberrant Cell Using Fluorescent Probe

Xuening Fei1*;Lijuan Liu1; Baolian Zhang1,2;Bojie Shi1;Kangde Yao2   

  1. 1. Materials Department of Tianjin Institute of Urban Construction, Tianjin 300384, China; 2. Research Institute of Polymeric Materials, Tianjin University, Tianjin 300072, China
  • Received: Revised: Online: Published:
  • Contact: Xuening Fei
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The structure characteristics of aberrant cell, identification marking, fluorescence labeling technologies and methods of cell labeling by fluorescent probe are recommended. The progress of research on labeling of aberrant cell tissue by fluorescent probe or by connecting with biologically active carrier is reviewed. Based on the applications in cell marking of fluorescent probe, the developing trends are described including approaches and methods of increasing the compatibility of fluorescent probe with bodies tissue, the validity for labeling towards the aberrant cell, improving the sensitivity and reducing toxicity of fluorescent probe. The advantage of preparation and purification of probe using solid-phase synthesis technology is prospected.
Key words: fluorescent probe, aberrant cell, recognition, label

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