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Progress in Chemistry 2006, Vol. 18 Issue (0203): 337-343 Previous Articles   Next Articles

• Review •

Quantum Dots：The New Development of FRET

Lingzhi Liu;Zhihong Liu*; Zhike He;Ruxiu Cai   

  1. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072,China
  • Received: Revised: Online: Published:
  • Contact: Zhihong Liu
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Fluorescence resonance energy transfer ( FRET) has broad applications in the study of the interactions of biological macromolecules, immunoassay, nucleic acid detection and so on. However many organic dyes conventionally used in FRET have functional limitations such as low resistance to photobleaching, narrow excitation bands coupled with broad emission bands, all of which have limited the development and the application of FRET. Therefore new pairs of energy donor and acceptor are needed. Because of the advantages over organic dyes,quantum dots (QDs) have expanded the range of FRET and have been considered as new and significant development trend of FRET nowadays. The theory of FRET and the applications of QDs in FRET are reviewed in this article.
Key words: fluorescence resonance energy transfer, quantum dots, biological macromolecules

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Abstract

Quantum Dots：The New Development of FRET