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Progress in Chemistry 2006, Vol. 18 Issue (01): 120-130 Previous Articles   

Special Issue: 计算化学

• Review •

Modeling Techniques of Multidimensional Quantitative Structure-Activity Relationship in Computer-Aided Drug Design

Guizhao Liang1;Hu Mei1;Yuan Zhou1;Zhiliang Li 1,2*   

  1. 1.  Key Laboratory of Biomechanics and Tissue Engineering, Ministry of Education (Chongqing University , Chongqing 400044,China); 2. College of Chemistry and Chemical  Engineering , Chongqing 400044, China
  • Received: Revised: Online: Published:
  • Contact: Zhiliang Li
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Multidimensional quantitative structure-activity relationship (MD QSAR) has been successfully applied as a crucial technique for computeraided drug design (CADD) in various fields. Based on plentiful literatures, different strategies and various methodologies of MD QSAR are systematically summarized by combining with research works in authors'  laboratory. Recent progress of MD QSAR in CADD is reviewed.

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