中文
Earlier issues
Announcement
More
Progress in Chemistry 2005, Vol. 17 Issue (06): 1054-1059 Previous Articles   Next Articles

• Review •

The Bioactivity of Glycocluster and Glycodendrimer

Lu Weishen1;Zhang Xiaoru2**   

  1. 1. Institute of Marine Drugs and Food,Ocean University of China,Qingdao 266003;

    2.College of Chemistry and Molecular Engineering,Qingdao University of Science & Technology,Qingdao 266042,China

  • Received: Revised: Online: Published:
  • Contact: Zhang Xiaoru
PDF ( 1844 ) Cited
Export

EndNote

Ris

BibTeX

A new type of glycoconjugate-glycocluster and glycodendrimer has been designed as mimics for the “multivalent effect”in nature. The recent advances in bioactivity of glycocluster and glycodendrimer and their potential applications are reviewed in this article.
Key words: carbohydrate, glycocluster, glycodendrimer, multivalent effect, bioactivity

CLC Number: 

[ 1 ] 叶新山(Ye X S) . 21 世纪有机化学发展战略(The Strategy on Organic Chemistry Development in the 21st Century) . 杜灿屏,刘鲁生, 张恒主编(eds. Du C P , Liu L S and Zhang H) . 北京: 化学工业出版社(Beijing : Chemical Industry Press ) ,2002. 307 —316
[ 2 ] Mammen M, Choi S K, Whitesides G M. Angew. Chem. Int .Ed. , 1998 , 37 : 2754 —2794
[ 3 ] Bertozzi C R , Kiessling L L. Science , 2001 , 291 (23) : 2357 —2364
[ 4 ] Davis B G. J . Chem. Soc. , Perkin Trans. 1 , 1999 , 3215 —3237
[ 5 ] Bezouíka K. Reviews in Molecular Biotechnology , 2002 , 90 :269 —290
[ 6 ] Gestwicki J E , Cairo C W, Strong L E , et al . J . Am. Chem.Soc. , 2002 , 124 : 14922 —14933
[ 7 ] 张晓茹(Zhang X R) , 李英霞(Li Y X) , 管华诗( Guan H S)等. 有机化学(Chin. J . Org. Chem. ) , 2004 , 24 (2) : 119 —126
[ 8 ] Lee Y C , Towsend R R , Hardy M R , et al . J . Biol . Chem. ,1983 , 258 : 199 —205
[ 9 ] Lindhorst T K, Dubber M, Krallmann-Wenzel U , et al . Eur. J .Org. Chem. , 2000 , 2027 —2034
[10] Kê tter S , Krallmann-Wenzel U , Lindhorst T K, et al . J . Chem.Soc. , Perkin Trans. 1 , 1998 , 2193 —2200
[11] Lindhorst T K, Kê tter S , Krallmann-Wenzel U , et al . J . Chem.Soc. , Perkin Trans. 1 , 2001 , 823 —831
[12] Ashton P R , Hounsell E F , Jayaraman N , et al . J . Org. Chem. ,1998 , 63 : 3429 —3437
[13] Reuter J D , Myc A , Hayes M M, et al . Bioconjugate Chem. ,1999 , 10 : 271 —278
[14] Furuike T , Aiba S , Suzuki T , et al . J . Chem. Soc. , Perkin Trans. 1 , 2000 , 3000 —3005
[15] Zanini D , Roy R. J . Org. Chem. , 1996 , 61 : 7348 —7354
[16] Meunier S J , Wang S N , Roy R. Can. J . Chem. , 1997 , 75 :1472 —1482
[17] Zanini D , Roy R. J . Org. Chem. , 1998 , 63 : 3486 —3491
[18] Sandvig K, Deurs B. The EMBOJournal , 2000 , 19(22) : 5943 —5950
[19] Kitov P I , Sadowska J M, Mulvey G, et al . Nature , 2000 , 403 :669 —672
[20] Fan E , Zhang Z S , Minke W E. J . Am. Chem. Soc. , 2000 ,122 : 2663 —2664
[21] Rice K G. in Glycosciences : Status and Perspectives (eds. Gabius HJ , Gabius S) . Weinheim: Chapman & Hall , 1997. 471 —483
[22] Lee Y C. Carbohydrate Recognition in Cellular Function ( eds.Bock G, Harnette S) . Chichester : Wiley , 1989. 80 —95
[23] Ozaki K, Lee R T , Lee Y C , Kawasaki T. Glycoconjuate J . ,1995 , 12 : 268 —274
[24] Hangeland J J , Levis J T , Lee Y C , et al . Bioconjugate Chem. ,1995 , 6 : 695 —701
[25] Kichler A , Schuber F. Glycoconjugate J . , 1995 , 12 : 275 —281
[26] Zhang X R , Li Y X, Chu S D , Guan H S. Chin. J . Chem. ,2004 , 22 (5) : 482 —486
[27] Toyokuni T , Singhal A K. Chem. Soc. Rev. , 1995 , 231 —242
[28] Springer G F. Science , 1984 , 224 : 1198 —1206
[29] Schwarz J B , Kuduk S D , Danishefsky SJ . J . Am. Chem. Soc. ,1999 , 121 : 2662 —2673
[30] Baek M G, Rittenhouse-Olson K, Roy R. Chem. Commun. ,2001 , 257 —258
[31] Roy R , Baek M G. Reviews in Molecular Biotechnology , 2002 ,90 : 291 —309
[32] Zhu T , Boons G J . J . Chem. Soc. , Perkin Trans. 1 , 1998 ,857 —861
[33] Fang J W, Li J , Chen X, et al . J . Am. Chem. Soc. , 1998 , 120(27) : 6635 —6638
[34] Hanessian S , Huynh H K, Reddy G V , et al . Tetrahedron ,2001 , 57 : 3281 —3290
[35] Wang J Q , Chen X, Wang P G, et al . J . Am. Chem. Soc. ,1999 , 121 : 8174 —8181
[36] Xian M, Fatima Z , Wang P G, et al . J . Comb. Chem. , 2004 ,6 : 126 —134
[37] Zhang W, Wang J Q , Wang G P , et al . J . Carbohydr. Chem. ,1999 , 18 (8) : 1009 —1017
[38] Wang J Q , Zhang B Y, Wang P G, et al . J . Carbohydr. Chem. ,2003 , 22 (6) : 347 —376
[39] 卢忆　(Lu Y P) , 蔡孟深(Cai M S) , 李中军(Li Z J ) 等. 化学学报(Acta Chimica Sinica) , 2002 , 60(2) : 360 —366
[40] Lu Y P , Li H , Cai M S , Li ZJ . Carbohydrate Research , 2001 ,334 : 289 —294
[41] 李玉文(Li Y W) . 博士论文(Ph D Dissertation) . 中国海洋大学(Ocean University of China) , 2004
[42] Gestwicki J E , Kiessling L L. Nature , 2002 , 415 : 81 —84
[1] Wu Qiaomei, Yang Qiyue, Zeng Xianhai, Deng Jiahui, Zhang Liangqing, Qiu Jiarong. Catalytic Conversion of Cellulose-Based Biomass to Diols [J]. Progress in Chemistry, 2022, 34(10): 2173-2189.
[2] Hanyu Zhang, Meng Liu, Xia Wu, Miao Liu, Decai Xiong, Xinshan Ye. Photo-/Electro-Driven Carbohydrate-Based Reactions [J]. Progress in Chemistry, 2020, 32(11): 1804-1823.
[3] Lvhua Liu, Yanyan Zheng*, Lifang Zhang, Chengdong Xiong. Bioactive Polyetheretherketone Implant Composites for Hard Tissue [J]. Progress in Chemistry, 2017, 29(4): 450-458.
[4] Hou hui, Sun Dequn. Conformational Restriction of Peptidomimetics in Drug Design [J]. Progress in Chemistry, 2015, 27(9): 1260-1274.
[5] Wang Kerang. Chiral Supramolecular Assemblies Based on Aromatic Molecules-Carbohydrate Conjugates and Their Applications [J]. Progress in Chemistry, 2015, 27(6): 775-784.
[6] Xiong Yuting, Li Minmin, Xiong Peng, Yang Meng, Qing Guangyan, Sun Taolei. Artificial Carbohydrate Receptors in Aqueous Media [J]. Progress in Chemistry, 2014, 26(01): 48-60.
[7] Guo Jiaxiao, Hou Xin. Recent Advances of Carbohydrate Microarrays [J]. Progress in Chemistry, 2011, 23(8): 1719-1727.
[8] Hu Suqin, Zhang Xiaodong, Xu Min, Sun Li. Application of Ionic Liquids in Biomass Utilization [J]. Progress in Chemistry, 2011, 23(4): 731-738.
[9] Shi Yugang, Cai Yan, Li Jianrong, Chu Yenho. Enzyme-Catalyzed Regioselective Synthesis of Carbohydrate Fatty Acid Esters in Ionic Liquids [J]. Progress in Chemistry, 2011, 23(11): 2247-2257.
[10] Li Yan, Wei Zuojun, Chen Chuanjie, Liu Yingxin. Preparation of 5-hydroxymethylfurfural by Dehydration of Carbohydrates [J]. Progress in Chemistry, 2010, 22(08): 1603-1609.
[11] Wang Hongmin Zhang Ping Huang Linjuan Wang Zhongfu. Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry(MALDI) Application in Carbohydrates Analysis [J]. Progress in Chemistry, 2009, 21(6): 1335-1343.
[12] . Immobilization Strategies for Carbohydrate Microarrays [J]. Progress in Chemistry, 2009, 21(04): 747-754.
[13]

Wang Yadan, Wang Fei, Miao Zhiwei**, Chen Ruyu**

. Chiral Phosphorus Ligands Derived from Carbohydrate Scaffolds for Asymmetric Catalysis [J]. Progress in Chemistry, 2008, 20(12): 1923-1932.
[14]

Ding Shanshan1 Cui Yuanlu1 Gong Zheng2 Yin Yuji2** Yao Kangde2

. Heparin for Growth Factor Delivery systems [J]. Progress in Chemistry, 2008, 20(12): 1998-2011.
[15] Sun Zicai|Wei Zheng**|Wei Kemei. Heparan sulfate: Structure, Function, modification and Synthesis [J]. Progress in Chemistry, 2008, 20(0708): 1136-1142.