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Progress in Chemistry 2004, Vol. 16 Issue (02): 299- Previous Articles   Next Articles

• Review •

Biodegradable Polymeric Scaffolds for Bone Tissue Engineering

Cui Junfeng;Yin Yuji;He Shulan;Yao Kangde**   

  1. (Research Institute of Polymeric Materials, Tianjin University, Tianjin 300072, China)
  • Received: Revised: Online: Published:
  • Contact: Yao Kangde
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Bone is under extensive investigation in tissue engineering. A number of biodegradable and bioresorbable materials, as well as scaffold designs, have been experimentally studied. Materials used as bone tissue engineering scaf-folds can be rigid or injectable.The research on the bone tissue engineering from polymeric scaffold point of view, including the requirement of biodegradable scaffolds for bone tissue engineering, biomaterials used in bone tissue engineering, scaffold design and fabrication, scaffold surface modification was reviewed in this paper.
Key words: bone tissue engineering, scaffolds, biodegradable, polymers, surface modification

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[ 1 ] Yannas I V , Burke J F. J . Biomed. Mater. Res. , 1980 , 14 :65 —81
[ 2 ] Yannas I V , Burke J F , Gordon P L , et al . J . Biomed. Mater.Res. , 1980 , 14 : 107 —132
[ 3 ] Dagalakis N , Flink J , Stasikelis P , et al . J . Biomed. Mater.Res. , 1980 , 14 : 511 —528
[ 4 ] Wolter J R , Meyer R F. Trans. Am. Ophthalnol . Soc. , 1984 ,82 : 187 —202
[ 5 ] Langer R , Vacanti J P. Science , 1993 , 260 : 920 —926
[ 6 ] Hutmacher D W. Biomaterials , 2000 , 21 : 2529 —2543
[ 7 ] Griffith L G, Naughton G. Science , 2002 , 295 : 1009 —1014
[ 8 ] Hench L L , Polak J M. Science , 2002 , 295 : 1014 —1017
[ 9 ] Biomedical Materials (ed. Yu Y T) . Tianjin : Tianjin University Press , 2000. 74 —115
[10] Basic and Clinical Research on Tissue Engineering (ed. Yang Z M) . Chengdu : Sichuan Science and Technology Press , 2000. 2 —10
[11] Tissue Engineering (ed. Yang Z M) . Beijing : Chemical Industry Press , 2002. 2 —4
[12] Bone Engineering (ed. Davis J E) . Toronto : Em Squared Incorporated , 1999. 435 —436
[13] Chapekar M S. J . Biomed. Mater. Res. (Appl . Biomater. ) ,2000 , 53 : 617 —620
[14] Burg K J L , Porter S , Kellan J F. Biomaterials , 2000 , 21 :2347 —2359
[15] Agrawal C M, Ray R B. J . Biomed. Mater. Res. , 2001 , 55 :141 —150
[16] Van de Putte KA , Urist M R. Clin. Orthop. Rel . Res. , 1965 ,43 : 257 —270
[17] Urist M R , Silverman B F , Burig K, et al . Clin. Orthop. Rel .Res. , 1967 , 53 : 243 —283
[18] Russell J L , Block J E. Orthopaedics , 1999 , 22 : 524 —531
[19] Chakkalakal D A , Strates B S , Mashoof A A , et al . Bone , 1999 ,25 (3) : 321 —332
[20] Groeneveld E H J , van den Bergh J P A , Holzmann P , et al . J .Biomed. Mater. Res. (Appl . Biomater. ) , 1999 , 8 : 393 —402
[21] Thalgott J S , Giuttre J M, Klezl Z, et al . Spine , 2002 , 2 : 63 —69
[22] Yaylaoglu M B , Yildiz C , Korkusuz F , et al . Biomaterials , 1999 ,20 : 1513 —1520
[23] Doi Y, Horiguchi T, Moriwaki Y, et al . J . Biomed. Mater.Res. , 1996 , 31 : 43 —49
[24] Du C , Cui F Z, Zhu X D , et al . J . Biomed. Mater. Res. ,I999 , 44 : 407 —415
[25] Bakos D , Soldan M, Hernandez-Fuentes I. Biomaterials , 1999 ,20 : 191 —195
[26] Itoh S , Kikuchi M, Koyama Y, et al . Biomaterials , 2002 , 23 :3919 —3926
[27] Madihally S V , Matthew H W T. Biomaterials , 1999 , 20 :1133 —1142
[28] Seong H , Bae H J , Kown I C , et al . Polymer Preprints , 2000 ,41 : 1687 —1688
[29] Leffler C C , Muller B W. Int . J . Pharm. , 2000 , 194 : 229 —237
[30] Klokkevdd P R , Vandemark L , Kenny F B , et al . J . Periodontol . , 1996 , 67 : 1170 —1175
[31] Zhang Y, Zhang M Q. J . Non-crystalline Solids , 2001 , 282 :159 —164
[32] Zhang Y, Zhang M. J . Biomed. Mater. Res. , Part A , 2001 ,55 : 304 —312
[33] Zhang Y, Zhang M. J . Biomed. Mater. Res. , Part A , 2002 ,62 : 378 —386
[34] Lee Y M, Park Y J , Lee S J , et al . J . Periodontol . , 2000 , 71 :410 —417
[35] Zhao F , Yin Y J , Lu W W, et al . Biomaterials , 2002 , 23 :3227 —3234
[36] Gutowska A , Jeong B , Jasionowski M. Anat . Rec. , 2001 , 263 :342 —349
[37] Langer R. Acc. Chem. Res. , 2000 , 33 : 94 —101
[38] Furukawa K S , Ushida T, Toita K, et al . Cell Transplant , 2002 ,11 : 475 —480
[39] Rutkowski G E , Heath C A. Biotechnol . Prog. , 2002 , 18 :362 —372
[40] Evans G R , Brandt K, Widmer M S , et al . Biomaterials , 1999 ,20 : 1109 —1115
[41] Tjia J S , Aneskievich B J , Moghe P V. Biomaterials , 1999 , 20 :2223 —2233
[42] Agrawal C M, Bert J , Heckman J D , et al . Biomaterials , 1995 ,16 : 1255 —1260
[43] Ishaug S L , Grane G M, Miller M J , et al . J . Biomed. Mater.Res. , 1997 , 36 : 17 —28
[44] Ishaug-Riley S L , Creme-Kruger G M, Yaszemski M J , et al . Biomaterials , 1998 , 19 : 1405 —1412
[45] Sakavitsas V I , Bancroft G N , Mikos A G. J . Biomed. Mater.Res. , Part A , 2002 , 62 : 136 —148
[46] Ibim S M, Uhrich K E , Bronson R , et al . Biomaterials , 1998 ,19 : 941 —951
[47] Ibim S E , Uhrich K E , Attawia M, et al . J . Biomed. Mater.Res. , 1998 , 43 : 374 —379
[48] Chiba M, Hanes J , Langer R. Biomaterials , 1997 , 18 : 893 —901
[49] Hanes J , Chiba M, Langer R. Biomaterials , 1998 , 19 : 163 —172
[50] Burkoth A K, Burdick J , Anseth K S. J . Biomed. Mater. Res. ,2000 , 51 : 352 —359
[51] Shen F , Kipper M J , Dziadul B , et al . J . Control . Release ,2002 , 82 : 115 —125
[52] Lemmaichi Y, Schacht E , Lootens C. J . Control . Release , 1998 ,55 : 79 —85
[53] Woo G L Y, Mittelnan M W, Santerre J P. Biomaterials , 2000 ,21 : 1235 —1246
[54] Chandy T, Wolson R F , Rao G H , et al . J . Biomater. Appl . ,2002 , 16 : 275 —291
[55] Lowry K J , Hanson K R , Bear L , et al . J . Biomed. Mater.Res. , 1997 , 36 : 536 —541
[56] Choueka J , Charvet J L , Koval K J , et al . J . Biomed. Mater.Res. , 1996 , 31 : 35 —41
[57] Ertel S I , Kohn J , Zimmerman M C , et al . J . Biomed. Mater.Res. , 1995 , 29 : 1337 —1348
[58] Yu C , Mielemczyk S S , Breslauer K J , et al . Biomaterials , 1999 ,20 : 265 —272
[59] Peter S J , Miller S T, Zhu G, et al . J . Biomed. Mater. Res. ,1998 , 41 : 1 —7
[60] Peter S J , Kin P , Yasko A W, et al . J . Biomed. Mater. Res. ,1999 , 44 : 314 —321
[61] Peter SJ , Lu L , Kin D J , et al . Biomaterials , 2000 , 21 : 1201 —1213
[62] Fisher J P , Vehof J W M, Dean D , et al . J . Biomed. Mater.Res. , 2002 , 59 : 547 —556
[63] Payne R G, McGonigle J S , Yaszemski M J , et al . Biomaterials ,2002 , 23 : 4381 —4387
[64] Chen G, Ushida T, Tateish T. Macromol . Biosci . , 2002 , 2 :67 —77
[65] Meinig R P , Rahn B , Perren S M, Gogoldewski S. J . Orthop.Trauma , 1996 , 10 : 178 —190
[66] Meinig R P , Buesing C M, Helm J , Gogoldewski S. J . Orthop.Trauma , 1997 , 11 : 551 —558
[67] Gugala Z, Gogolewski S. J . Orthop. Trauma , 1999 , 13 : 187 —195
[68] Gugala Z, Gogolewski S. Injury , 2002 , 33 (S 2) : 71
[69] Thomson R C , Yaszemski M J , Powers J M, et al . J . Biomater.Sci . Polym. Ed. , 1995 , 7 : 23 —38
[70] Thomson R C , Yaszemski M J , Powers J M, et al . Biomaterials ,1998 , 19 : 1935 —1943
[71] Ishaug S L , Yaszemski M J , Bizios R , et al . J . Biomed. Mater.Res. , 1994 , 28 : 1445 —1453
[72] Ishaug S L , Grane G M, Miller M J , et al . J . Biomed. Mater.Res. , 1997 , 36 : 17 —28
[73] Peter S J , Miller M J , Yaosko A W, et al . J . Biomed. Mater.Res. (Appl . Biomater. ) , 1998 , 43 : 422 —427
[74] Temenoff J S , Mikos A G. Biomaterials , 2000 , 21 : 2405 —2412
[75] Peter S J , Yaszemski M J , Suggs L J , et al . J . Biomater. Sci .Polym. Ed. , 1997 , 8 : 893 —904
[76] He S , Timmer M D , Yaszemski M J , et al . Polymer , 2001 , 42 :1251 —1260
[77] He S , Yaszemski M J , Yasko A W, et al . Biomaterials , 2000 ,21 : 2389 —2394
[78] Frazier D D , Lathi V K, Gerhart T N , et al . J . Biomed. Mater.Res. , 1997 , 35 : 383 —389
[79] Gresser J D , Hsu S H , Nagaoka H , et al . J . Biomed. Mater.Res. , 1995 , 29 : 1241 —1247
[80] Kharas G B , Kemenetsky M, Simantirakis J , et al . J . Apply.Polym. Sci . , 1997 , 66 : 1123 —1137
[81] Timmer M D , Ambrose C G, Mikos A G. Biomaterials , 2003 ,24 : 571 —577
[82] Yaszenski M J , Payne R G, Hayes W C , et al . Biomaterials ,1996 , 17 : 2127 —2130
[83] Yaszenski M J , Payne R G, Hayes W C. Tissue Eng. , 1995 , 1 :41 —52
[84] Jo S , Shin H , Mikos A G. Biomacromolecules , 2001 , 2 : 255 —261
[85] Shin H , Jo S , Mikos A G. J . Biomed. Mater. Res. , 2002 , 61 :169 —179
[86] Vehof J W M, Fisher J P , Dean D. J . Biomed. Mater. Res. ,2002 , 60 : 241 —251
[87] Goldstein A S , Juarez T M, Helmke C D. Biomaterials , 2001 ,22 : 1279 —1288
[88] Wineternantel E , Mayer J , Blum J , et al . Biomaterials , 1996 ,17 : 83 —91
[89] Shakesheff K, Cannizzaro S , Langer R. J . Biomater. Sci . Polym.Ed. , 1998 , 9 : 507 —518
[90] Rezania A , Healy K E. Biotechnol . Prog. , 1999 , 15 : 19 —32
[91] Burdick J A , Anseth K S. Biomaterials , 2002 , 23 : 4315 —4323
[92] Cai K Y, Yao K D , Cui Y L. J . Biomed. Mater. Res. , 2002 ,60 : 398 —404
[93] Cai K Y, Yao K D , Li Z. J . Biomater. Sci . Polym. Ed. , 2001 ,12 : 1303 —1315
[94] Cai K Y, Yao K D , Cui Y L. Biomaterials , 2002 , 23 : 1603 —1611
[95] Cai K Y, Yao K D , Lin S B. Biomaterials , 2002 , 23 : 1153 —1160
[96] Cai K Y, Yao K D , Hou X. J . Biomed. Mater. Res. , 2002 ,62 : 283 —291
[97] Yang J , Bei J Z, Wang S G. Biomaterials , 2002 , 23 : 2607 —2614
[98] Yang J , Bei J Z, Wang S G, et al . J . Biomed. Mater. Res. ,2002 , 62 : 438 —446
[99] Zhu Y B , Gao C Y, Shen J C. Biomaterials , 2002 , 23 : 4889 —4895
[100] Zhu Y B , Gao C Y, Liu X Y, et al . Biomacromolecules , 2002 ,3 : 1312 —1319
[101] Zhu H G, Ji J , Gao C Y, et al . Biomaterials , 2002 , 23 : 3141 —3148
[102] Zhu H G, Ji J , Gao C Y, et al . J . Biomed. Mater. Res. , 2002 ,62 : 532 —539
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