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Progress in Chemistry 2004, Vol. 16 Issue (02): 284- Previous Articles   Next Articles

• Review •

Application of Silicon Linkers in Solid-Phase Organic Synthesis

Han Yongbin;Li Yi**;Yang Guoqiang   

  1. (Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101, China; Laboratory of Photochemistry, Center for Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, China)
  • Received: Revised: Online: Published:
  • Contact: Li Yi;Yang Guoqiang
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The concept of solid-phase synthesis has been realized by more and more chemists. The linker plays a crucial role in solid-phase synthesis. Many efforts have been done on the development of new linkers. The organosilyl linkers which have been developed for more than 20 years are according with conditions of ideal linkers antl have the po-tential for development in the future. This paper with 29 references reviewed the design, synthesis and applications of organosilyl linkers in solid phase synthesis within 26 years.
Key words: solid phase synthesis, organosilicon, linker

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