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Progress in Chemistry 2002, Vol. 14 Issue (04): 279- Previous Articles   Next Articles

• Review •

Biological Effects of Vanadium and Its Potential for Pharmaceutical Applications-The Chemical Issues in the Studies on Metal Drugs

Yang Xiaogai;Yang Xiaoda;Wang Kui*   

  1. Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University， Beijing 100083, China
  • Received: Revised: Online: Published:
  • Contact: Wang Kui
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In light of the analogy in chemical and biological behavior between non-essential ions and essential ions, the chemical species of vanadium compounds under physiological condition and their physical-chemical characters, which are important for the biological effects are reviewed. The mechanisms of hypoglycemic activity of insulin-mimic vanadium compounds and development of anti-diabetes drugs are also introduced.
Key words: vanadium, insulin, diabetes, biological effects, analogy

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