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Progress in Chemistry 2000, Vol. 12 Issue (04): 423- Previous Articles   Next Articles

• Review •

Chemical Biology: A Rapidly Rising Frontier

Wu Houming   

  1. Sate Key Laboratory of Bioorganic and Natural Products Chemistry,Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,Shanghai 200032, China
  • Received: Revised: Online: Published:
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Chemical biology is rapidly establishing itself as an important interdisciplinary field through crosslink and fusion. Chemical tools and methods, such as synthetic, structural and analytical ones, are used to study biological and medical problems. The molecular biology means are also accepted to resolve problems in chemistry as well. The main research strategy in this new area is to alter the function of biological molecules and to explore the molecular mechanism of molecular recognition and signal pathway involved in physiological and pathological processes using small natural or designed molecules as probes. The explosion of the knowledge at the interface of chemistry, biology and medicine not only supplies powerful approaches for clarifying details and regulation mechanism of cellular processes and better understanding of life at molecular level, but also new opportunities for the creation and development of novel medicines.
Key words: chemical biology, interdisciplinary field, small molecule regulation

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