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Progress in Chemistry 2000, Vol. 12 Issue (01): 63- Previous Articles   Next Articles

• Review •

Progress in Synthesis and Structural Modification of Huperzine A

Zeng Fanxing;Jiang Hualiang;Yang Yushe;Chen Kaixian;Ji Ruyun**   

  1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China
  • Received: Revised: Online: Published:
  • Contact: Ji Ruyun
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Huperzine A has been shown to be a powerful selective inhibitor of acetylcho linesterase and has at tracted widespread at tention because of its unique pharmacological profile and low toxicity. The total chemical synthesis, structural modification and structure activity relation ship of huperzine A have been systematically reviewed
Key words: huperzine A, total chemical synthesis, structural modification, activity

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