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Progress in Chemistry 1998, Vol. 10 Issue (04): 442- Previous Articles   Next Articles

• Review •

Three-Dimensional Structure Searching in Drug Design

Wang Ting;Zhou Jiaju   

  1. Laboratory of Computer Chemistry , Institute of Chemical Metallurgy,Chinese Academy of Sciences, Beijing 100080, China
  • Received: Revised: Online: Published:
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Three-dimensional(3D) searching in a database of molecules based on their 3D characteristics has become a fast and effecive approach to discover leading compounds.This review describes its principle, development and applications in drug design.

Key words: 3D searching, drug design, conformational searching

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