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Progress in Chemistry 1998, Vol. 10 Issue (04): 427- Previous Articles   Next Articles

• Review •

Computer Modeling for Interaction of Ligands and Receptors and Their Applications in Drug Design

Jiang Hualiang;Hu Zengjian;Chen Jianzhong;Gu Jiande;Zhu Weiliang;Chen Kaixian;Ji Ruyun   

  1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China
  • Received: Revised: Online: Published:
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The interaction of ligands with their receptor macromolecules are central to most of biological processes. Nowadays, there are accumulating evidences of that ligand-receptor interaction can be simulated with computer modeling and theoretical calculation methods. Some of these methods and their applications in drug design were reviewed in this paper.

Key words: ligand-receptor interaction, molecularmodeling, theoretical calculation, drug design

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