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Progress in Chemistry 1998, Vol. 10 Issue (04): 395- Previous Articles   Next Articles

• Review •

Cleavage of Nucleic Acids by Lanthanides and Their Complexes

Zhu Bing;Zhao Daqing;Ni Jiazuan   

  1. Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
  • Received: Revised: Online: Published:
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Artificial nucleases are compounds that cleave nucleic acids and function as natural restriction enzymes with high activity and selectivity. They consist of nucleic acid recognition and catalytic scission systems, and can mimic the natural restriction enzymes by combining these two functions. This paper describes the cleavage of nucleic acids by lanthanides and their complexes and the acting mechanism.

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