• Review •
Zhang Ruoheng; Wang Hong; Xu Xiaojie
Received:
Revised:
Online:
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Contact:
Zhang Ruoheng, Wang Hong, Xu Xiaojie
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Based on the sequence-specific DNA-binding protein and DNA cleaving agents,complex of a chelator and an appropriate metal ion,sequence-specific DNA cleaving proteins were designed and synthesized. The DNA cleaving agents were directed to DNA by attachment to a DNA-binding protein,and the resulting protein may be used as a sequence--specific DNA cleaving protein.