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Progress in Chemistry 2024, Vol. 36 Issue (1): 18-26 DOI: 10.7536/PC230507 Previous Articles   Next Articles

• Review •

Application of Nanozymes in the Treatment of Brain Diseases

Ziying Meng1, Jie Wang1, Jiapu Wang1, Yan Wei1,2, Di Huang1,2, Ziwei Liang1,2()   

  1. 1 College of Biomedical Engineering, Taiyuan University of Technology, Research Center for Nano-Biomaterials & Regenerative Medicine, Taiyuan 030024, China
    2 Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering, Taiyuan 030024, China
  • Received: Revised: Online: Published:
  • Contact: * e-mail: liangziweiguozhong@163.com
  • Supported by:
    National Natural Science Foundation of China(82103147); National Natural Science Foundation of China(12272253); Natural Science Foundation of Shanxi Province, China(20210302124007); Natural Science Foundation of Shanxi Province, China(202203021221047); Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering(2021SX-AT008); Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering(2021SX-AT009)
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In recent years, nanozymes, as a new generation of artificial enzymes, have gradually entered the medical field due to their multi-enzyme activity, high stability and targeting ability, which are superior to natural enzymes. Moreover, nanozymes have been applied to the treatment of a variety of diseases and cancer because of their regulatory effect on reactive oxygen species. Brain diseases, as one of the highest mortality diseases, are prone to produce complex inflammatory responses due to excessive reactive oxygen species in the pathological environment. Therefore, the application of nanozymes in the brain environment may become an effective means of monitoring and treatment of brain diseases. This article reviews the principles of nanozymes in the treatment of brain diseases and the current research status in this field in recent years, including nanozymes inducing cancer cell death by regulating the level of reactive oxygen species, nanozymes assisting traditional anticancer therapy, nanozymes using membrane proteins to monitor brain cancer, and their applications in traumatic brain injury, stroke, brain degenerative diseases, cerebral malaria and epilepsy. At the end of this text, the problems of its application in clinical treatment are discussed.

Contents

1 Introduction

2 Development of researches about nanozymes

3 Application of nanozymes in the treatment of brain cancer and brain diseases

3.1 Nanozymes in brain cancer

3.2 Nanozymes in degenerative disease

3.3 Nanozymes in other brain diseases

4 Conclusion and outlook

Key words: nanozymes, ROS, brain cancer, brain injury, Alzheimer’s disease
Table 1 Advantages of some nanozymes compared with native enzymes[15???~19]
Types Advantage ref
Graphene and its derivatives Large specific surface areas; rich surface chemistry 15
CeO2 nanoparticles Multiple catalytic activities 15
BSA-Au cluster Good stability and high biocompatibility in water solution 16
FeN3P-SAzyme Comparable peroxidase-like catalytic activity and kinetics to natural enzymes 17
Boron-doped Fe-N-C single-atom nanozymes Vivid mimicking nature peroxidase 18
MNx Efficient multienzyme-mimetic catalysis with good selectivity; 4 and 5-fold higher affinities in peroxidase-like activity than the FeN4 and natural horseradish peroxidase; Higher affinity in the catalase-like activity 19
Fig. 1 Nanozymes are involved in brain cancer therapy via ROS
[1]
Quader S, Kataoka K, Cabral H. Adv. Drug Deliv. Rev., 2022, 182: 114115.

doi: 10.1016/j.addr.2022.114115
[2]
Jiang F, Yang J M, Zhang Y T, Dong M, Wang S X, Zhang Q Y, Liu F F, Zhang K, Zhang C. Nat. Rev. Cardiol., 2014, 11(7): 413.

doi: 10.1038/nrcardio.2014.59 pmid: 24776703
[3]
Kuriakose D, Xiao Z C. Int. J. Mol. Sci., 2020, 21(20): 7609.

doi: 10.3390/ijms21207609
[4]
Hou Y X, Zhang R F, Yan X, Fan K L. Sci. Sin. Vitae, 2020, 50(3): 311.

doi: 10.1360/SSV-2019-0216
(侯亚欣, 张若飞, 阎锡蕴, 范克龙. 中国科学(生命科学), 2020, 50(3): 311.)
[5]
Wei H, Gao L Z, Fan K L, Liu J W, He J Y, Qu X G, Dong S J, Wang E K, Yan X Y. Nano Today, 2021, 40: 101269.

doi: 10.1016/j.nantod.2021.101269
[6]
Jansman M M T, Hosta-Rigau L. Catalysts, 2019, 9(8): 691.

doi: 10.3390/catal9080691
[7]
Zhu M Y, Dai Y Q, Wu Y N, Liu K, Qi X M, Sun Y M. Nanotechnology, 2018, 29(46): 465704.

doi: 10.1088/1361-6528/aaddc2
[8]
Sharifi M, Hosseinali S H, Yousefvand P, Salihi A, Shekha M S, Aziz F M, JouyaTalaei A, Hasan A, Falahati M. Mater. Sci. Eng. C, 2020, 108: 110422.

doi: 10.1016/j.msec.2019.110422
[9]
Tang R Y, Xia X M, Zhang X, Jiang H, Wang B H, Zhang P L, Zhang Y J, Tang Y X, Zhou Y. Spectrochimica Acta A Mol. Biomol. Spectrosc., 2022, 266: 120467.
[10]
Ding H, Hu B, Zhang B, Zhang H, Yan X Y, Nie G H, Liang M M. Nano Res., 2021, 14(3): 570.

doi: 10.1007/s12274-020-3053-9
[11]
Sun H J, Zhou Y, Ren J S, Qu X G. Angew. Chem. Int. Ed., 2018, 57(30): 9224.

doi: 10.1002/anie.v57.30
[12]
Niu X H, Li X, Lyu Z Y, Pan J M, Ding S C, Ruan X F, Zhu W L, Du D, Lin Y H. Chem. Commun., 2020, 56(77): 11338.

doi: 10.1039/D0CC04890A
[13]
Zhang R F, Fan K L, Yan X Y. Sci. China Life Sci., 2020, 63(8): 1183.
[14]
Jiang D W, Ni D L, Rosenkrans Z T, Huang P, Yan X Y, Cai W B. Chem. Soc. Rev., 2019, 48(14): 3683.

doi: 10.1039/C8CS00718G
[15]
Lin Y H, Ren J S, Qu X G. Acc. Chem. Res., 2014, 47(4): 1097.

doi: 10.1021/ar400250z
[16]
Wang X X, Wu Q, Shan Z, Huang Q M. Biosens. Bioelectron., 2011, 26(8): 3614.

doi: 10.1016/j.bios.2011.02.014
[17]
Ji S F, Jiang B, Hao H G, Chen Y J, Dong J C, Mao Y, Zhang Z D, Gao R, Chen W X, Zhang R F, Liang Q, Li H J, Liu S H, Wang Y, Zhang Q H, Gu L, Duan D M, Liang M M, Wang D S, Yan X Y, Li Y D. Nat. Catal., 2021, 4(5): 407.

doi: 10.1038/s41929-021-00609-x
[18]
Jiao L, Xu W Q, Zhang Y, Wu Y, Gu W L, Ge X X, Chen B B, Zhu C Z, Guo S J. Nano Today, 2020, 35: 100971.

doi: 10.1016/j.nantod.2020.100971
[19]
Zhang S F, Li Y H, Sun S, Liu L, Mu X Y, Liu S H, Jiao M L, Chen X Z, Chen K, Ma H Z, Li T, Liu X Y, Wang H, Zhang J N, Yang J, Zhang X D. Nat. Commun., 2022, 13: 4744.

doi: 10.1038/s41467-022-32411-z
[20]
Manea F, Houillon F B, Pasquato L, Scrimin P. Angew. Chem. Int. Ed., 2004, 43(45): 6165.

doi: 10.1002/anie.v43:45
[21]
Gao L Z, Zhuang J, Nie L, Zhang J B, Zhang Y, Gu N, Wang T H, Feng J, Yang D L, Perrett S, Yan X Y. Nat. Nanotechnol., 2007, 2(9): 577.

doi: 10.1038/nnano.2007.260
[22]
Gao L Z, Liang M M, Wen T, Wei H, Zhang Y, Fan K L, Jiang B, Qu X G, Gu N, Pang D W, Xu H Y, Yan X Y. China Terminology, 2020, 22(06): 21.
(高利增, 梁敏敏, 温涛, 魏辉, 张宇, 范克龙, 江冰, 曲晓刚, 顾宁, 庞代文, 许海燕, 阎锡蕴. 中国科技术语, 2020, 22(06): 21.)
[23]
Wei H, Wang E K. Chem. Soc. Rev., 2013, 42(14): 6060.

doi: 10.1039/c3cs35486e
[24]
Gao L Z, Chen L, Zhang R F, Yan X Y. Sci. Sin. Chim., 2022, 52(09): 1649.

doi: 10.1360/SSC-2022-0088
(高利增, 陈雷, 张若飞, 阎锡蕴. 中国科学:化学, 2022, 52(09): 1649.)
[25]
Fan K L, Gao L Z, Wei H, Jiang B, Wang D J, Zhang R F, He J Y, Meng X Q, Wang Z R, Fan H Z, Wen T, Duan D M, Chen L, Jiang W, Lu Y, Jiang B, Wei Y H, Li W, Yuan Y, Dong H J, Zhang L, Hong C Y, Zhang Z X, Cheng M M, Geng X, Hou T Y, Hou Y X, Li J R, Tang G H, Zhao Y, Zhao H Q, Zhang S, Xie J Y, Zhou Z J, Ren J S, Huang X L, Gao X F, Liang M M, Zhang Y, Xu H Y, Qu X G, Yan X Y. Progress in Chemistry, 2023, 35(1): 1.
(范克龙, 高利增, 魏辉, 江冰, 王大吉, 张若飞, 贺久洋, 孟祥芹, 王卓然, 樊慧真, 温涛, 段德民, 陈雷, 姜伟, 芦宇, 蒋冰, 魏咏华, 李唯, 袁野, 董海姣, 张鹭, 洪超仪, 张紫霞, 程苗苗, 耿欣, 侯桐阳, 侯亚欣, 李建茹, 汤国恒, 赵越, 赵菡卿, 张帅, 谢佳颖, 周子君, 任劲松, 黄兴禄, 高兴发, 梁敏敏, 张宇, 许海燕, 曲晓刚, 阎锡蕴. 化学进展, 2023, 35(01): 1.).
[26]
Cheng H J, Zhang L, He J, Guo W J, Zhou Z Y, Zhang X J, Nie S M, Wei H. Anal. Chem., 2016, 88(10): 5489.

doi: 10.1021/acs.analchem.6b00975
[27]
Liu J, Zhang W, Peng M H, Ren G Y, Guan L H, Li K, Lin Y Q. ACS Applied Materials & Interfaces., 2020, 12(26): 29631.
[28]
Wang C, Wang M C, Zhang W, Liu J, Lu M J, Li K, Lin Y Q. Anal. Chem., 2020, 92(1): 662.

doi: 10.1021/acs.analchem.9b04931
[29]
Reczek C R, Chandel N S. Annu. Rev. Cancer Biol., 2017, 1: 79.

doi: 10.1146/annurev-cancerbio-041916-065808
[30]
Kwon S, Ko H, You D G, Kataoka K, Park J H. Acc. Chem. Res., 2019, 52(7): 1771.

doi: 10.1021/acs.accounts.9b00136
[31]
Aguilera-Márquez J D R, de Dios-Figueroa G T, Reza-Saldivar E E, Camacho-Villegas T A, Canales-Aguirre A A, Lugo-Fabres P H. Neurol. Perspect., 2022, 2: S31.
[32]
Mansur A A P, Mansur H S, Carvalho S M. Catal. Today, 2022, 388/389: 187.

doi: 10.1016/j.cattod.2020.06.083
[33]
Zou Z Z, Chang H C, Li H L, Wang S M. Apoptosis, 2017, 22(11): 1321.

doi: 10.1007/s10495-017-1424-9
[34]
Liu S L, Zhang W, Chen Q Q, Hou J X, Wang J R, Zhong Y X, Wang X Y, Jiang W X, Ran H T, Guo D J. Nanoscale, 2021, 13(33): 14049.

doi: 10.1039/D1NR01449H
[35]
Mansur A A P, Carvalho S M, Oliveira L C A, Souza-Fagundes E M, Lobato Z I P, Leite M F, Mansur H S. Pharmaceutics, 2022, 14(10): 2223.

doi: 10.3390/pharmaceutics14102223
[36]
Fan K L, Xi J Q, Fan L, Wang P X, Zhu C H, Tang Y, Xu X D, Liang M M, Jiang B, Yan X Y, Gao L Z. Nat. Commun., 2018, 9: 1440.

doi: 10.1038/s41467-018-03903-8
[37]
Muhammad P, Hanif S, Li J, Guller A, Rehman F U, Ismail M, Zhang D, Yan X, Fan K, Shi B. Nano Today, 2022, 45:101530.

doi: 10.1016/j.nantod.2022.101530
[38]
Wang S R, Wang Z Y, Li Z Y, Zhang X G, Zhang H T, Zhang T, Meng X X, Sheng F G, Hou Y L. Sci. Adv., 2022, 8(21): eabn3883.

doi: 10.1126/sciadv.abn3883
[39]
Zhu X F, Chen X, Huo D L, Cen J Q, Jia Z, Liu Y A, Liu J. Biomaterials Science., 2021, 9(15): 5330.

doi: 10.1039/D1BM00667C
[40]
Voth B, Nagasawa D T, Pelargos P E, Chung L K, Ung N, Gopen Q, Tenn S, Kamei D T, Yang I. Journal Of Clinical Neuroscience., 2015, 22(7): 1071.

doi: 10.1016/j.jocn.2015.02.002
[41]
Daniels T R, Delgado T, Helguera G, Penichet M L. Clin. Immunol., 2006, 121(2): 159.

doi: 10.1016/j.clim.2006.06.006 pmid: 16920030
[42]
Weerathunge P, Pooja D, Singh M, Kulhari H, Mayes E L H, Bansal V, Ramanathan R. Sens. Actuat. B Chem., 2019, 297: 126737.

doi: 10.1016/j.snb.2019.126737
[43]
Kip Ç, Akbay E, Gökçal B, Savaş B O, Ali Onur M, Tuncel A. Colloids Surf. A Physicochem. Eng. Aspects, 2020, 598: 124812.

doi: 10.1016/j.colsurfa.2020.124812
[44]
Chen Q S, Liu Y B, Liu J B, Liu J W. Chem. Eur. J., 2020, 26(70): 16659.

doi: 10.1002/chem.v26.70
[45]
Huang W, Xia Q, Zheng F, Zhao X, Ge F, Xiao J, Liu Z, Shen Y, Ye K, Wang D, Li Y. JAD, 2023, 221064.
[46]
Ren C X, Li D D, Zhou Q X, Hu X G. Biomaterials, 2020, 232: 119752.

doi: 10.1016/j.biomaterials.2019.119752
[47]
Gong Y C, Huang A L, Guo X, Jia Z, Chen X, Zhu X F, Xia Y, Liu J, Xu Y, Qin X Y. Chem. Eng. J., 2021, 418: 129345.

doi: 10.1016/j.cej.2021.129345
[48]
Jia Z, Yuan X Y, Wei J A, Guo X, Gong Y C, Li J, Zhou H, Zhang L, Liu J. ACS Appl. Mater. Interfaces, 2021, 13(42): 49602.

doi: 10.1021/acsami.1c06687
[49]
Bai Z T, Ge K Z, Fu J J, Yu D H, Hua Z Y, Xue S L, Li Z, Sheng W W, Wu X N, Gao F F, Geng D Q, Gao F L. Chem. Eng. J., 2023, 465: 142955.

doi: 10.1016/j.cej.2023.142955
[50]
Isaev N K, Stelmashook E V, Genrikhs E E. Rev. Neurosci., 2020, 31(3): 233.

doi: 10.1515/revneuro-2019-0052
[51]
Du C J, Feng W, Dai X Y, Wang J H, Geng D Y, Li X D, Chen Y, Zhang J. Small, 2022, 18(39): 2203031.

doi: 10.1002/smll.v18.39
[52]
Lyu Z Y, Ding S C, Zhang N, Zhou Y, Cheng N, Wang M Y, Xu M J, Feng Z X, Niu X H, Cheng Y, Zhang C, Du D, Lin Y H. Research, 2020, 2020: 4724505.
[53]
Padilla-Godínez F J, Ruiz-Ortega L I, Guerra-Crespo M. Cells, 2022, 11(21): 3445.

doi: 10.3390/cells11213445
[54]
Singh N, Savanur M A, Srivastava S, D'Silva P, Mugesh G. Angewandte Chemie Int. Ed., 2017, 56(45): 14267.

doi: 10.1002/anie.v56.45
[55]
Wang W, Zheng J Y, Zhou H, Liu Q, Jia L, Zhang X M, Ge D T, Shi W, Sun Y N. ACS Appl. Mater. Interfaces, 2022, 14(29): 32901.

doi: 10.1021/acsami.2c06981
[56]
Li L H, Lu Y, Xu X Y, Yang X F, Chen L L, Jiang C M, Wang Y, Hu W Y, Wei X M, Yang Z M. Adv. Healthcare Mater., 2021, 10(13): 2100316.

doi: 10.1002/adhm.v10.13
[57]
Zhu Z Q, Gong L B, Miao X Y, Chen C Y, Su S. Biosensors, 2022, 12(5): 260.

doi: 10.3390/bios12050260
[58]
Xia Z H, Gao M M, Sheng P, Shen M M, Zhao L, Gao L Z, Yan B C. Int. J. Mol. Sci., 2022, 23(12): 6463.

doi: 10.3390/ijms23126463
[59]
Yu D Q, Ma M M, Liu Z W, Pi Z F, Du X B, Ren J S, Qu X G. Biomaterials, 2020, 255: 120160.

doi: 10.1016/j.biomaterials.2020.120160
[60]
Wang C, Ren G Y, Yuan B B, Zhang W, Lu M J, Liu J, Li K, Lin Y Q. Anal. Chem., 2020, 92(11): 7822.

doi: 10.1021/acs.analchem.0c01028
[61]
Abdul-Muneer P M, Chandra N, Haorah J. Mol. Neurobiol., 2015, 51(3): 966.

doi: 10.1007/s12035-014-8752-3 pmid: 24865512
[62]
Bains M, Hall E D. Biochim. Biophys. Acta BBA Mol. Basis Dis., 2012, 1822(5): 675.
[63]
Mu X Y, He H, Wang J Y, Long W, Li Q F, Liu H L, Gao Y L, Ouyang L F, Ren Q J, Sun S, Wang J Y, Yang J, Liu Q, Sun Y M, Liu C L, Zhang X D, Hu W P. Nano Lett., 2019, 19(7): 4527.

doi: 10.1021/acs.nanolett.9b01333
[64]
Mu X Y, Wang J Y, He H, Li Q F, Yang B, Wang J H, Liu H L, Gao Y L, Ouyang L, Sun S, Ren Q J, Shi X J, Hao W T, Fei Q M, Yang J, Li L L, Vest R, Wyss-Coray T, Luo J, Zhang X D. Sci. Adv., 2021, 7(46): eabk1210.

doi: 10.1126/sciadv.abk1210
[65]
Yan R J, Sun S, Yang J, Long W, Wang J Y, Mu X Y, Li Q F, Hao W T, Zhang S F, Liu H L, Gao Y L, Ouyang L F, Chen J C, Liu S J, Zhang X D, Ming D. ACS Nano, 2019, 13(10): 11552.

doi: 10.1021/acsnano.9b05075
[66]
Zhang S F, Liu Y, Sun S, Wang J Y, Li Q F, Yan R J, Gao Y L, Liu H L, Liu S J, Hao W T, Dai H T, Liu C L, Sun Y M, Long W, Mu X Y, Zhang X D. Theranostics, 2021, 11(6): 2806.

doi: 10.7150/thno.51912
[67]
He H, Shi X J, Wang J Y, Wang X J, Wang Q, Yu D Y, Ge B S, Zhang X D, Huang F. ACS Appl. Mater. Interfaces, 2020, 12(1): 209.

doi: 10.1021/acsami.9b17509
[68]
Xi J Q, Zhang R F, Wang L M, Xu W, Liang Q, Li J Y, Jiang J, Yang Y L, Yan X Y, Fan K L, Gao L Z. Adv. Funct. Mater., 2021, 31(9): 2007130.

doi: 10.1002/adfm.v31.9
[69]
Liu Y S, Wang X J, Li X Z, Qiao S S, Huang G D, Hermann D M, Doeppner T R, Zeng M L, Liu W, Xu G L, Ren L J, Zhang Y, Liu W L, Casals E, Li W P, Wang Y C. ACS Appl. Mater. Interfaces, 2021, 13(39): 46213.

doi: 10.1021/acsami.1c06449
[70]
Huang Z X, Qian K, Chen J, Qi Y, Yifeng E, Liang J, Zhao L. Acta Biomater., 2022, 144: 142.

doi: 10.1016/j.actbio.2022.03.018
[71]
Huang G N, Zang J K, He L Z, Zhu H L, Huang J R, Yuan Z W, Chen T F, Xu A D. ACS Nano, 2022, 16(1): 431.

doi: 10.1021/acsnano.1c07205
[72]
Tian R Z, Ma H Y, Ye W, Li Y J, Wang S P, Zhang Z R, Liu S D, Zang M S, Hou J X, Xu J Y, Luo Q, Sun H C, Bai F Q, Yang Y, Liu J Q. Adv. Funct. Mater., 2022, 32(36): 2204025.

doi: 10.1002/adfm.v32.36
[73]
Yan B C, Cao J W, Liu J J, Gu Y H, Xu Z B, Li D D, Gao L Z. ACS Biomater. Sci. Eng., 2021, 7(1): 299.

doi: 10.1021/acsbiomaterials.0c01312
[74]
Feng L S, Dou C R, Xia Y G, Li B H, Zhao M Y, Yu P, Zheng Y Y, El-Toni A M, Atta N F, Galal A, Cheng Y S, Cai X J, Wang Y, Zhang F. ACS Nano, 2021, 15(2): 2263.

doi: 10.1021/acsnano.0c07973
[75]
Zhao Q Q, Du W X, Zhou L L, Wu J R, Zhang X X, Wei X E, Wang S J, Huang Y, Li Y H. Pharmaceutics, 2022, 14(6): 1122.

doi: 10.3390/pharmaceutics14061122
[76]
Zhao S, Duan H X, Yang Y L, Yan X Y, Fan K L. Nano Lett., 2019, 19(12): 8887.

doi: 10.1021/acs.nanolett.9b03774
[77]
Prabhu P, Suryavanshi S, Pathak S, Patra A, Sharma S, Patravale V. Int. J. Pharm., 2016, 513(1/2): 504.
[78]
Stafstrom C E, Carmant L. Cold Spring Harbor Perspectives In Medicine., 2015, 5(6): 022426.
[79]
Wang N, Zhang M R, Ma Y P, Liu S Y, Liu Q Q, Liao Y H, Ding F, Tian X M. Journal Of Nanoparticle Research., 2021, 23(12): 266.

doi: 10.1007/s11051-021-05381-4
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