The rapid hemostasis and healing of wounds have a very important effect on human life security and physical health. During the treatment process of wounds, careful, targeted, and effective treatment is required to prevent infection and accelerate tissue regeneration. Thus, the research on wound care materials attracted much attention. Among them, bio-based polymer materials extracted from animals and plants or synthesized from bio-based monomers, having the advantages of good physical properties, biological activity, biocompatibility, biodegradability and bioabsorbability, have been modified or drug-loaded by physical or chemical methods to produce hemostatic materials and wound dressings with functions of hemostasis, sterilization, protection and promotion of wound healing. Herein, we review the progress of domestic and foreign research on hemostatic materials and wound dressings based on common bio-based polymers, such as polylactic acid, chitosan, sodium alginate, hyaluronic acid, protein and polyphosphate in recent years from multiple angles of chemical composition, synthetic route, preparation method, material structure, evaluation model and biological activity. And the research level at home and abroad on these hemostatic materials from bio-sourced and renewable natural resources is also analyzed and compared. Predictably, the main research directions will still be further broadening the types of raw materials as well as making multifunctional and biomimetic materials.

Contents

1 Introduction

2 Polylactic acid materials

2.1 Polylactic acid

2.2 Polylactic acid-Polyethylene glycol

2.3 Poly(lactic acid-co-glycolic acid)

2.4 Other modified PLAs

3 Polysaccharides

3.1 Chitosans

3.2 Alginates

3.3 Hyaluronic acids

3.4 Celluloses

4 Proteins and polypeptides

5 Polyphosphates

6 Conclusion and outlook