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Progress in Chemistry 2016, Vol. 28 Issue (10): 1489-1500 DOI: 10.7536/PC160314 Previous Articles   Next Articles

Synthesis and Application of Water-Soluble Conjugated Glycopolymer

Sun Pengfei1,2, Hou Huanzhi1, Fan Quli1*, Huang Wei1,3*   

  1. 1. Key Laboratory for Organic Electronics & Information Displays and Institute of Advanced Materials, Jiangsu Synergetic Innovation Center for Advanced Materials, Nanjing University of Posts & Telecommunications, Nanjing 210023, China;
    2. State Key Laboratory of Molecular Engineering of Polymers, Shanghai 200433;
    3. Jiangsu Key Laboratory of Flexible Electronics and the Synergetic Innovation Center for Advanced Materials, Nanjing Tech University, Nanjing 211816, China
  • Received: Revised: Online: Published:
  • Supported by:
    The work was supported by the National Natural Science Foundation of China (No. 61378081, 21574064), The Jiangsu Provincial Natural Science Foundation for Youth(No. BK20150843), NUPTSF(No.NY215017), and The State Key Laboratory of Molecular Engineering of Polymers Program(No.K2016-17).
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Water-soluble conjugated polymers (WSCPs) have been applied to a wide range of fields such as chemical sensing, bio-sensing and bio-imaging. The advantages of WSCPs for these applications include their high brightness, good photo-stability, structure variety and sufficient solubility in aqueous solution. WSCPs are usually decorated with water-soluble ionic groups or polymers on their sides or end groups. Sugars are a kind of biomolecules existing naturally and most of them have the features of water-solubility, therefore in recent years researchers have introduced sugar compounds into conjugated polymers leading to water-soluble conjugated glycopolymers with the biological properties of carbonhydrates. In this review, we summarize the recent development in the synthesis of water-soluble conjugated glycopolymers and their applications in terms of lectin-sensing, bacteria-sensing and live-cell imaging. Finally, we point out the peculiarity, developing trend and the challenges of water-soluble conjugated glycopolymers.

Contents
1 Introduction
2 Water-soluble conjugated polymers with sugar side-chains
2.1 PDA-based water-soluble conjugated glycopolymers
2.2 PPE-based water-soluble conjugated glycopolymers
2.3 PT-based water-soluble conjugated glycopolymers
2.4 Others water-soluble conjugated glycopolymers
3 Amphiphilic conjugated glycopolymers
4 Conclusion

Key words: water-soluble conjugated polymers, glycopolymer, fluorescence detection, lectin

CLC Number: 

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