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Progress in Chemistry 2016, Vol. 28 Issue (4): 528-540 DOI: 10.7536/PC150913 Previous Articles   Next Articles

• Review and comments •

Recent Advances of the Water-Soluble Conjugated Polymer Brushes

Lu Xiaomei1*, Li Jie1, Hu Wenbo2, Deng Weixing2, Fan Quli2, Huang Wei1,2*   

  1. 1. Key Laboratory of Flexible Electronics & Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing Tech University, Nanjing 211816, China;
    2. Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials, Jiangsu National Synergetic Innovation Center for Advanced Materials, Nanjing University of Posts & Telecommunications, Nanjing 210023, China
  • Received: Revised: Online: Published:
  • Supported by:
    The work was supported by the National Basic Research Program of China(973)(No. 2012CB723402)and the National Natural Science Foundation of China(No. 21222404, 51173080, 21104033, 21574064).
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Water-soluble conjugated polymers (WSCPs) have been widely used in chemical and biological sensing owning to their intriguing optoelectronic and biocompatible properties. However, these linear WSCPs suffer from the general drawbacks of low water-solubility and fluorescence quantum efficiency. Polymer brushes is a kind of unique macromolecules with a linear polymeric backbone and densely grafted side chains. Developing water-soluble conjugated polymer brushes (WSCPBs) is highly anticipated to solve the above mentioned problems. This article reviews the synthetic protocol and structure-properties relationship of WSCPBs to guide the design and preparation of new WSCPBs. In addition, we highlight the applications of WSCPBs in terms of sensor, bioimaging, drug delivery and surfactant. Finally, the future opportunities and challenges of WSCPBs are discussed.

Contents
1 Introduction
2 The synthesis of water-soluble conjugated polymer brushes
2.1 Grafting from approach
2.2 Grafting onto approach
2.3 Grafting through approach
3 Structure-properties relationship of water-soluble conjugated polymer brushes
3.1 Effects of conjugated backbone
3.2 Effects of graft side chains
4 Application of water-soluble conjugated polymer brushes
4.1 Sensor
4.2 Bioimaging
4.3 Drug delivery
4.4 Surfactant
5 Conclusion and outlook

Key words: water-solubility, molecule brush, conjugated polymer, bioimaging

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