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Progress in Chemistry 2015, Vol. 27 Issue (11): 1658-1664 DOI: 10.7536/PC150429 Previous Articles   Next Articles

• Review and comments •

Studying on the Mechanisms of NH3/NH4+through Ammonium Transport Proteins

Zhang Mingming, Fan Jianfen*, Yu Yi, Yan Xiliang, Xu Jian   

  1. College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, China
  • Received: Revised: Online: Published:
  • Supported by:
    The work was supported by the National Natural Science Foundation of China(No.21173154)and the National Key Basic Research and Development Program of China(973 Program)(No.2012CB825803).
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Ammonium transport proteins widely exist in various life forms including bacteria, fungi, plants, animals, etc. The transport of NH3/NH4+ through an ammonium transport protein has been widely studied. However, the issue that the ionic NH4+ or the electrically neutral NH3 species truly goes through the hydrophobic pore of an ammonium transport protein remains controversial. This review surveys the progress in studying on the transport mechanisms of NH3/NH4+ through several typical ammonium transport proteins. The main mechanisms include the single transport of NH3 or NH4+, and the cooperative transport of NH3 and H+, etc.

Contents
1 Introduction
2 NH3 transport mechanism
3 NH4+ transport mechanism
4 Cooperative transport of NH3 and H+
5 Other transport mechanisms
6 Conclusion

Key words: ammonium transport protein, NH3/NH4+ transmembrane transport, biological channel, mechanism

CLC Number: 

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