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Progress in Chemistry 2013, Vol. 25 Issue (06): 1023-1030 DOI: 10.7536/PC121106 Previous Articles   Next Articles

• Review •

Preparation and Application of Zwitterionic Polymers

He Xiaoyan*, Zhou Wenrui, Xu Xiaojun, Yang Wu*   

  1. College of Chemistry and Chemical Engineering, Northwest Normal University, Key Lab of Bioelectrochemistry & Environmental Analysis of Gansu Province, Lanzhou 730070, China
  • Received: Revised: Online: Published:
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Because of their unique pendant-side chain structures, zwitterionic polymers present excellent chemical properties, preferable thermal stability and hydration capacity, especially the anti-polyelectrolyte behavior in solution, have attracted broad attention in the world in recent years. Due to the hydrophilic functional groups such as -OH, -COOH and -SO3H present in the molecular structure, zwitterionic polymers are capable of resisting non-specific protein adsorption,bacterial adhesion and blood coagulation even from undiluted blood plasma and serum.Many novel and functional zwitterionic polymers have been synthesized and attracted a great deal of interest in such fields as petroleum industry, biomedical materials, drug synthesis and sewage treatment. In this review, recent progress in the structure, properties, synthesis methods, applications and developing prospects of zwitterionic polymers are summarized, specifically their synthesis methods and applications. We hope it can be helpful for the research and development of the zwitterionic polymers. Contents
1 Introduction
2 Characteristic and classification of polymers
3 Preparation of zwitterionic polymers
3.1 Copolymerization of one or more monomers
3.2 Functionalization of the polymers
4 Application of zwitterionic polymers
4.1 Application of zwitterionic polymers in the petroleum industry
4.2 Application of zwitterionic polymers in the anti-protein pollution
4.3 Application of zwitterionic polymers in drug controlled release
5 Conclusion and outlook

Key words: zwitterionic polymers, anti-polyelectrolyte behavior, radical polymerization, drug release

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[1] Andrew B L, Charles L M. Chem. Rev., 2002, 102: 4177-4189
[2] Liu J S, Zhan Y, Xu T G, Shao G Q. J. Membrane Sci., 2008, 325: 495-502
[3] Liu J S, Xu T W, Han X Z, Fu Y X. Eur. Polym. J., 2006, 42: 2755-2764
[4] Liu J S, Ma Y, Xu T G, Shao G Q. J. Hazard. Mater., 2010, 178: 1021-1029
[5] Liu J S, Song L, Shao G Q. J. Chem. Eng., 2011, 56: 2119-2127
[6] Xuan F Q, Liu J S. Polym. Int., 2009, 58: 1350-1361
[7] 景峰(Jing F), 黄荣华(Huang R H). 高分子材料科学与工程(Polymer Materials Science and Engineering), 1997, 13: 109-113
[8] Salamone J C, Volksen W, lsrael S C, Olson A P, Raia D C. Polymer, 1977, 18: 1058-1062
[9] McCormick C L, Johnson C B. Macromolecules, 1988, 21: 686-693
[10] McCormick C L, Johnson C B. Macromolecules, 1988, 21: 694-699
[11] 张黎明(Zhang L M). 高分子通报(Polymer Bulletin), 1998, 4: 80-85
[12] Peter K, Andre L, Vladimir T. Makromol. Chem., 1992, 193: 1815-1827
[13] Krzysztof M, Nicolay V. Nat. Chem., 2009, 1: 276-288
[14] 李强(Li Q), 张丽芬(Zhang L F), 柏良久(Bo L J), 缪洁(Miao J), 程振平(Cheng Z P), 朱秀林(Zhu X L). 化学进展(Progress in Chemistry), 2010, 22(11): 2080-2088
[15] 杨正龙(Yang Z L), 周丹(Zhou D), 陈秋云(Chen Q Y). 化学进展(Progress in Chemistry), 2011, 23(11): 2360-2367
[16] 游倩倩(You Q Q), 张普玉(Zhang P Y), 张怀敏(Zhang H M), 庄玉伟(Zhuang Y W). 化学研究(Chemical Research), 2012, 23(2): 94-99
[17] 胡俊祺(Hu J Q), 董智贤(Dong Z X), 崔艳艳(Cui Y Y), 刘晓暄(Liu X X). 高分子通报(Polymer Bulletin), 2012, 5: 47-54
[18] 郑海洪(Zheng H H), 李建波(Li J B), 罗庆英(Luo Q Y). 天然气勘探与开发(Natural Gas Exploration and Development), 2009, 32(3): 59-62
[19] Dobbins S C, McGrath D E, Bernards M T. J. Phys. Chem. B, 2012, 116: 14346-14352
[20] Salamone J C, Watterson A C, Hsu T D, Tsai C C, Mahmud M U. Polym. Lett., 1977, 15: 487-491
[21] Abdelgawad R, George O. J. Appl. Polym. Chem., 1977, 15: 469-488
[22] Salamone J C, Rodriguez E L, Lin K C, Quach L, Watterson A C, Ahmed I. Polymer, 1985, 26: 1234-1238
[23] Salamone J C, Quach L, Watterson A C, Krauser S, Mahmud M U. J. Macromol. Sci. Chem., A22 (5/7): 1985, 653-664
[24] Joan F D, Khadidja B, Mustapha R, Jean P B, Jack H. Catal. Commun., 2002, 3: 185-190
[25] Galin M, Chapoton A, Galin J C. J. Chem. Soc. Perkin Trans., 1993, 2: 545-553
[26] Salamone J C, Volksen W, Israel S C, Olson A P, Raia D C. Polymer, 1977, 18: 1058-1062
[27] 丁伟(Ding W), 毛程(Mao C), 韦兆水(Wei Z S), 李明(Li M), 于涛(Yu T), 曲广淼(Qu G M). 应用化学(Applied Chemistry), 2012, 5: 555-559
[28] 丁伟(Ding W), 毛程(Mao C), 于涛(Yu T), 刘宏彬(Liu H B), 曲广淼(Qu G M), 化工科技(Science Technology in Chemical Industry), 2010, 18(5): 15-19
[29] Brault N D, Sundaram H S, Li Y T, Huang C J, Yu Q M, Jiang S Y. Biomacromolecules, 2012, 13: 589-593
[30] Lalani R, Liu L Y. Biomacromolecules, 2012, 13: 1853-1863
[31] Sun J T, Yu Z Q, Hong C Y, Pan C Y. Macromol. Rapid Commun., 2012, 33: 811-818
[32] Wu L, Jasinski J, Krishnan S. Appl. Polym. Sci., 2012, 124: 2154-2170
[33] Kim M, Kim J C, Rho Y, Jung J, Kwon W, Kim H, Ree M. J. Mater. Chem., 2012, 22: 19418-19428
[34] Yang R, Gleason K K. Langmuir, 2012, 28: 12266-12274
[35] Philippe F, Laschewsky A. Macromol. Chem. Phys., 1999, 200: 887-895
[36] 李娟(Li J), 王中华(Wang Z H), 胡群爱(Hu Q A). 油田化学(Oilfield Chemistry), 2011, 2: 229-235
[37] Kuang J H, Phillip B M. Langmuir, 2012, 28: 7258-7266
[38] 石卿(Shi Q), 苏延磊(Su Y L), 姜忠义(Jiang Z Y). 中国科技论文(China Sciencepaper), 2010, 5: 172-175
[39] Li Y, Giesbers M, Gerth M, Zuilhof H. Langmuir, 2012, 28: 12509-12517
[40] Chen S F, Li L Y, Zhao C, Zheng J. Polymer, 2010, 51: 5283-5293
[41] Ai T N, Jacob B, Jos M J P, Cees J M, Han Z. Langmuir, 2011, 27: 2587-2594
[42] Jiang S Y, Cao Z Q. Adv. Mater., 2010, 22: 920-932
[43] Ladd J, Zhang Z, Chen S F, Jason C H, Jiang S Y. Biomacromolecules, 2008, 9(5): 1357-1361
[44] Huang C J, Li Y T, Jiang S Y. Anal. Chem., 2012, 84: 3440-3445
[45] Cheng G, Li G Z, Xue H, Chen S F, Bryers J D, Jiang S Y. Biomaterials, 2009, 30: 5234-5240
[46] Zhang L, Xue H, Gao C L, Carr L, Wang J N, Chu B C, Jiang S Y. Biomaterials, 2010, 31: 6582-6588
[47] Li G, Cheng G, Xue H, Chen S F, Zhang F B, Jiang S Y. Biomaterials, 2008, 29: 4592-4597
[48] Huang C J, Mi L, Jiang S Y. Biomaterials, 2012, 33: 3626-3631
[49] Cao Z Q, Zhang L, Jiang S Y. Langmuir, 2012, 28: 11625-11632
[50] Nguyen A T, Baggerman J, Paulusse J M J, Rijn C J M, Zuilhof H. Langmuir, 2011, 27: 2587-2594
[51] 李建华(Li J H), 李弥滋(Li M Z), 张其清(Zhang Q Q), 许小平(Xu X P). 功能材料(Functional Materials), 2012, 13: 1748-1751
[52] Li Q, Bi Q Y, Zhou B, Wang X L. Appl. Surf. Sci., 2012, 258: 4707-4717
[53] Yuan Y Y, Mao C Q, Du X J, Du J Z, Wang F, Wang J. Adv. Mater., 2012, 24: 5476-5480
[54] 杜翠鸣(Du C M), 王坤余(Wang K Y), 刘白玲(Liu B L), 苏德强(Su D Q). 皮革科学与工程(Leather Science and Engineering), 2007, 17: 37-42
[55] Lee W F, Huang G Y. Polymer, 1996, 37( 19): 4389-4395
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