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Progress in Chemistry 2020, Vol. 32 Issue (2/3): 179-189 DOI: 10.7536/PC190802 Previous Articles   Next Articles

Design and Application of pH Sensitive and Intelligent Hydrogels

Qiuling Yu1, Zheng Li1,3,**(), Chunyan Dou1, Yiping Zhao2, Jixian Gong1,**(), Jianfei Zhang1,4   

  1. 1. Key Laboratory of Advanced Textile Composites of Ministry of Education, School of Textiles Science and Engineering, Tiangong University, Tianjin 300387, China
    2. School of Material Science and Engineering, Tiangong University, Tianjin 300387, China
    3. Innovation Research Institute of Wolfberry Industry Co. LTD, Zhongning 755199, China
    4. Collaborative Innovation Center for Eco-Textiles of Shandong Province, Qingdao 266071, China
  • Received: Online: Published:
  • Contact: Zheng Li, Jixian Gong
  • About author:
    ** e-mail: (Zheng Li);
    (Jixian Gong)
  • Supported by:
    National Key Research and Development Project Foundation of China(2017YFB0309800); National Key Research and Development Project Foundation of China(2016YFC0400503-02); Xinjiang Autonomous Region Major Significant Project Foundation(2016A03006-3); Tianjin Natural Science Foundation(18JCYBJC89600); Science and Technology Guidance Project of China National Textile and Apparel Council(2017011); Innovation Research Institute of Wolfberry Industry Co. LTD(ZNGQCX-B-2019006)
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As a cross-linked three-dimensional network of hydrophilic polymer materials, hydrogels have similar characteristics to biological tissues and can absorb a large amount of water. As a kind of smart hydrogel, pH-sensitive hydrogel has a certain amount of pH sensitivity due to its structure containing a large number of basic or acidic groups. With these properties, such hydrogels have attracted much attention of researchers in many research fields such as biology, medicine, physics, environment and textiles in recent years. This review mainly focuses on three aspects: the response mechanism, classification and application of pH-sensitive hydrogels. Firstly, the response mechanism of pH sensitivity is reviewed from three aspects: response process, influencing factors and swelling-diffusion model. According to the pH sensitivity of such hydrogel, it can be divided into two types: swelling-shrinking type and sol-gel type. Further, the swelling-shrinking type can be divided into three types: anionic, cationic and amphoteric ionic according to the pH working range of such hydrogel, and the sol-gel type can be divided into borates, hydrazine and imines. In the field of applied research, this article summarizes the research status of such hydrogels in some popular fields such as medicine, environment, biology, intelligent monitoring and functional materials. Finally, the future of such hydrogel is prospected.

Key words: pH sensitivity, intelligent hydrogel, response mechanism, classification
Fig.1 pH sensitive hydrogels volume change with the pH of solution[17]
Fig.2 Hydrogel synthesis of ligin-grafted polyacrylate by enzymatic hydrolysis[40]
Fig.3 Schematic diagram of the structure change of LC/PAA polymer network with pH value change[45]
Fig.4 Photographs that demonstrate the macroscopic pH-induced shape memory behaviour of Dns-PAAM hydrogel[53]. (a) Original shape at pH=2.0. (b) Temporary shape at pH=5.0. (c~l) Transition from temporary shape to original shape at pH=2.0 in 10 min.
Fig.5 Schematic diagram of GO/CS hydrogel network structure[56]
Fig.6 Preparation process of PAAc/PDMAEMA hydrogel[58]
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