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Progress in Chemistry 2018, Vol. 30 Issue (8): 1133-1142 DOI: 10.7536/PC180115 Previous Articles   Next Articles

• Review •

Microfluidic Synthesis of Micro-and Nanoparticles

Yihuan Liu1, Xin Hu2, Ning Zhu1*, Kai Guo1*   

  1. 1. College of Biotechnology and Pharmaceutical Engineering, State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing Tech University, Nanjing 211800, China;
    2. College of Materials Science and Engineering, Nanjing Tech University, Nanjing 211800, China
  • Received: Revised: Online: Published:
  • Supported by:
    The work was supported by the National Natural Science Foundation of China(No. 21878145, 21504039, 21604037, 21522604).
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Micro-and nanoparticles with unique properties have broad applications in drug delivery, absorption separation, optical/electrical materials, and magnetic device, etc. Due to the huge volume-to-surface ratio and continuous flow characteristic, remarkable advantages have been made in organic chemistry, polymer synthesis and material preparation by employing microfluidic technology compared with the traditional batch reactor. This review summarizes the recent progress in microfluidic synthesis of micro-and nanoparticles. Microreactor system can precisely monitor and control the particle formation process. By using single emulsion as the template, spherical and non-spherical polymer/inorganic/noble metal/semiconductor particles are fabricated. Multi-emulsions are used as templates for fabricating core shell particles, Janus particles and microcapsules.
Contents
1 Introduction
2 Particle assembly in dispersed phase of single emulsions
2.1 Spherical particles
2.2 Non-spherical particles
3 Particle assembly in dispersed phase of multi-emulsions
3.1 Core-shell particles
3.2 Janus particles
3.3 Microcapsules
4 Conclusion
Key words: microfluidic, nanoparticles, microparticles, drops, functionalized materials

CLC Number: 

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