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化学进展 2004, Vol. 16 Issue (05): 696- 前一篇   后一篇

• 综述与评论 •

核磁共振技术(NMR)在组合化学中的应用

姚念环;贺文义;刘刚*;Kit S. Lam   

  1. (中国医学科学院中国协和医科大学药物研究所 北京 100050

    University of California, Davis Cancer Center, 4501 X Street, Sacramento, California 95817, USA)

  • 收稿日期:2003-08-01 修回日期:2004-01-01 出版日期:2004-10-14 发布日期:2004-10-14
  • 通讯作者: 刘刚
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导出 被引次数 ( 3 | 1 )

Applications of Nuclear Magnetic Resonance Spectroscopy (NMR) to Combinatorial Chemistry

Yao Nianhuan;He Wenyi;Liu Gang*;Kit S. Lam   

  1. (Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union College of Medicine, Beijing 100050, China

    University of California, Davis Cancer Center, 4501 X Street, Sacramento, California 95817, USA)

  • Received:2003-08-01 Revised:2004-01-01 Online:2004-10-14 Published:2004-10-14
  • Contact: Liu Gang
对科学产生最大影响的分析方法是核磁共振技术(NMR),它被广泛用于许多领域.本文结合作者的研究结果评述了NMR在组合化学中的应用,着重于NMR在固相合成的应用、液态NMR和NMR在高通量筛选中的应用.
关键词： 核磁共振技术(NMR), 固相合成, 液态NMR, 高通量筛选
The analytical method that has the greatest impact on science is nuclear magnetic resonance spectroscopy. It is widely used in amny fields. Combining author's research, the applications of nuclear magnetic resonance spectroscopy (NMR) to combinatorial chemistry, including applications of NMR to solid phase synthesis, analysis in solution and screening by NMR are reviewed.
Key words: nuclear magnetic resonance spectroscopy, solid phase synthesis, solution-state NMR, high-throughput screening

中图分类号: 

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