English
新闻公告
More
化学进展 2022, Vol. 34 Issue (2): 239-240 DOI: 10.7536/PC220220   后一篇

所属专题: 中国化学印记

• 中国化学印记 •

手性纳米材料的免疫佐剂效应

曲广波, 江桂斌*()   

  1. 中国科学院生态环境研究中心 北京100085
  • 出版日期:2022-02-20 发布日期:2022-04-12
  • 通讯作者: 江桂斌

Immune Adjuvant Effect of Chiral Nanomaterials

Guangbo Qu, Guibin Jiang()   

  1. Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
  • Online:2022-02-20 Published:2022-04-12
  • Contact: Guibin Jiang

The chirality of nanoparticles determines their interaction with immune cells and the corre-spondent response in immune system. This finding provides a novel strategy for the design of vaccines to fight the infection of virus.

()
[1]
O'Hagan D T, Friedland L R, Hanon E, Didierlaurent A M. Curr. Opin. Immunol., 2017, 47: 93.

doi: S0952-7915(16)30107-8     pmid: 28755542
[2]
Petrovsky N, Aguilar J. C. Immunol. Cell Biol., 2004, 82 (5): 488.
[3]
Marrack P, McKee A S, Munks M W. Nat. Rev. Immunol., 2009, 9 (4): 287.

doi: 10.1038/nri2510     URL    
[4]
Xu L, Wang X, Wang W, Sun M, Choi W J, Kim J-Y, Hao C, Li S, Qu A, Lu M, Wu X, Colombari F M, Gomes W R, Blanco A L, de Moura A F, Guo X, Kuang H, Kotov N A, Xu C. Nature, 2022, 601 (7893): 366.

doi: 10.1038/s41586-021-04243-2     URL    
[5]
Hooftman A, O'Neill L A J. Nature, 2022, 601 (7893): 323.

doi: 10.1038/d41586-021-03806-7     URL    
[6]
Clausi A L, Merkley S A, Carpenter J F, Randolph T W. J. Pharm. Sci., 2008, 97 (6): 2049.

doi: 10.1002/jps.21143     URL    
[7]
Pulliam J R C, van Schalkwyk C, Govender N, von Gottberg A, Cohen C, Groome M J, Dushoff J, Mlisana K, Moultrie H. medRxiv, 2021: DOI: 10.1101/2021.11.11.21266068.

doi: 10.1101/2021.11.11.21266068    
[8]
Schmidt F, Muecksch F, Weisblum Y, Silva J D, Bednarski E, Cho A, Wang Z, Gaebler C, Caskey M, Nussenzweig M C, Hatziioannou T, Bieniasz P D. medRxiv 2021, DOI: 10.1101/2021.12.12.21267646.

doi: 10.1101/2021.12.12.21267646    
No related articles found!
阅读次数
全文


摘要

手性纳米材料的免疫佐剂效应