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化学进展 2013, Vol. 25 Issue (09): 1415-1420 DOI: 10.7536/PC121262 前一篇   后一篇

• 癌症化学预防专辑 •

中国癌症流行病学与防治研究现状

曾红梅, 陈万青*   

  1. 中国医学科学院肿瘤医院 全国肿瘤防治研究办公室 北京100021
  • 收稿日期:2012-12-01 修回日期:2013-06-01 出版日期:2013-09-25 发布日期:2013-07-31
  • 通讯作者: 陈万青 E-mail:chenwq@cicams.ac.cn
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Cancer Epidemiology and Control in China：State of the Art

Zeng Hongmei, Chen Wanqing*   

  1. National Office for Cancer Prevention and Control, Chinese Academy of Medical Sciences, Cancer Hospital & Institute, Beijing 100021, China
  • Received:2012-12-01 Revised:2013-06-01 Online:2013-09-25 Published:2013-07-31

癌症是影响我国居民健康的主要慢性病之一,列城市死因的第一位,农村死因的第二位。本文对我国近几十年来癌症的流行状况、发病负担进行了概述。结果显示由于我国老龄人口的增加,消化道癌症发病负担依然严重,而与环境和生活方式密切相关的癌症如肺癌、乳腺癌等近年来显著增加。预计在未来几十年内,我国癌症发病率和死亡率将整体继续呈上升趋势。沉重的癌症负担需要采用综合化的防治策略来解决。本文阐述了我国的癌症防治政策、体系建设和癌症数据监测情况,介绍了近几十年来在我国癌症高发现场开展病因学预防及早诊早治工作的历史经验,概述了全国范围内癌症防控现状,为今后癌症防治工作提供参考。

关键词： 癌症, 趋势分析, 预防控制, 癌症筛查

Cancer has been a major challenge for public health in China. It ranks first among all causes of death in urban areas, and second in rural areas. This paper present the latest cancer statistics of China. The incident number of gastrointestinal cancers is still high and the burden of lung cancer and breast cancer are increasing. The trend indicates that the overall cancer burden would still be severe with the rapid development of China and aging population. Addressing this challenge requires comprehensive and multidisciplinary approaches. The current status of cancer control polices, structures, and cancer registration in China are described. National cancer control plans has been carried out by Ministry of Health since 1986. National program of cancer registry has been set up. In 2012, the number of population-based cancer registries has expanded to 222, covering populations with 200 millions. In areas with high risk of cancer, they have held systematic programs of cancer control. Many places such as Linzhou and Cixian have shown a down-trend of cancer incidence and mortality. The successful experiences in areas of high risk of cancer also promote the nationwide cancer campaign. The prevention programs include tobacco control, immunization against hepatitis B for infants and children, and cancer early detection and diagnosis. This paper provides considerable scope and motivation for future work on cancer control and prevention.

Contents
1 Introduction
2 Cancer statistics
3 The current status of cancer prevention and control
3.1 Strategies and policies for cancer control and prevention
3.2 Systematic construction for cancer related agencies
3.3 Cancer registry and surveillance
3.4 Experiences of cancer control in areas with high risk of cancer
3.5 Nationwide cancer control programs
4 Conclusion and outlook

Key words: cancer, trend analysis, prevention and control, cancer screening

中图分类号: 

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[1] 陈竺(Chen Z). 全国第三次死因回顾抽样调查报告(The Third National Death Survey Report). 北京:中国协和医科大学出版 社(Beijing: Peking Union Medical College Publication House), 2008. 11—12
[2] Wang J B, Jiang Y, Liang H, Li P, Xiao H J, Ji J, Xiang W, Shi J F, Fan Y G, Li L, Wang D, Deng S S, Chen W Q, Wei W Q, Qiao Y L, Boffetta P. Ann. Oncol., 2012, 23(11): 2983—2989
[3] 赫捷(He J), 陈万青(Chen W Q). 2012年中国肿瘤登记年报 (Chinese Cancer Registry Annual Report 2012). 北京:军事医学 科学出版社(Beijing: Press of Military Medical Sciences), 2012. 21—39
[4] 陈万青(Chen W Q),郑荣寿(Zheng R S),曾红梅(Zeng H M), 张思维(Zhang S W),赵平(Zhao P),赫捷(He J). 中华肿瘤杂 志(Chinese Journal of Oncology), 2012, 34(7): 517—524
[5] 曾红梅(Zeng H M),郑荣寿(Zheng R S),张思维(Zhang S W),赵平(Zhao P),赫捷(He J),陈万青(Chen W Q). 中华肿 瘤杂志(Chinese Journal of Oncology), 2012, 34(7): 525—531
[6] 陈万青(Chen W Q), 邹小农(Zou X N). 中国肿瘤(China Cancer), 2008, 17(9): 794—796
[7] 中国慢性病防治工作规划(2012—2015年). National Program for Chronic Disease Control and Prevention (2012—2015)[2012-12-24]. http://www.moh.gov.cn/publicfiles/business/ htmlfiles/mohjbyfkzj/s5878/201205/54755.htm.
[8] 中国癌症防治行动计划调研组(Investigation Group of Action Plan for Cancer Prevention and Control in China). 中国肿瘤 (China Cancer), 2012, 21(9): 641—643
[9] 陈竺(Chen Z). 中国卫生产业(China Health Industry), 2012, 9(1): 2
[10] 唐辉(Tang H),马洁(Ma J). 癌症进展(Cancer Progress), 2010, 8(2): 202—204
[11] 张思维(Zhang S W), 陈万青(Chen W Q), 王乐(Wang L). 中国 肿瘤(China Cancer), 2009, 18(4): 256—259
[12] 游伟程(You W C). 中国肿瘤(China Cancer), 2011, 20(1): 14—17
[13] You W C, Brown L M, Zhang L, Li J Y, Jin M L, Chang Y S, Ma J L, Pan K F, Liu W D, Hu Y, Crystal-Mansour S, Pee D, Blot W J, Fraumeni J F Jr, Xu G W, Gail M H. J. Natl. Cancer Inst., 2006, 98(14): 974—983
[14] Ma J L, Zhang L, Brown L M, Li J Y, Shen L, Pan K F, Liu W D, Hu Y, Han Z X, Crystal M S, Pee D, Blot W J, Fraumeni J F Jr, You W C, Gail M H. J. Natl. Cancer Inst., 2012, 104(6):488—492
[15] Wong B C Y, Zhang L, Ma J L, Pan K F, Li J Y, Shen L, Liu W D, Feng G S, Zhang X D, Li J, Lu A P, Xia H H, Lam S, You W C. Gut, 2012, 61(6): 812—818
[16] Qiao Y L, Dawsey S M, Kamangar F, Fan J H, Abnet C C, Sun X D, Johnson L L, Gail M H, Dong Z W, Yu B, Mark S D, Taylor P R. J. Natl. Cancer Inst., 2009, 101(7): 507—518
[17] Limburg P J, Wei W, Ahnen D J, Qiao Y, Hawk E T, Wang G, Giffen C A, Wang G, Roth M J, Lu N, Korn E L, Ma Y, Caldwell K L, Dong Z, Taylor P R, Dawsey S M. Gastroenterology, 2005, 129(3): 863—873
[18] Blot W J, Li J Y, Taylor P R, Guo W, Dawsey S, Wang G Q, Yang C S, Zheng S F, Gail M, Li G Y, Yu Y, Liu B Q, Tangrea J, Sun Y H, Liu F S, Fraumeni J F, Zhang Y H Jr, Li B. J. Natl. Cancer Inst., 1993, 85(18): 1483—1492
[19] 董志伟(Dong Z W), 乔友林(Qiao Y L), 王贵齐(Wang G Q), 张 苏展(Zhang S Z), 游伟程(You W C), 钱耕荪(Qian S G), 唐步坚 (Tang B J), 周清华(Zhou Q H), 李纪宾(Li J B), 杨娟(Yang J), 李 光琳(Li G L), 吴良有(Wu L Y), 孔灵芝(Kong L Z). 中华肿瘤杂 志(Chinese Journal of Oncology), 2012, 34(8): 637—640
[20] 陈建国(Chen J G), 朱健(Zhu J), 张永辉(Zhang Y H), 陈永胜 (Chen Y S), 丁璐璐(Ding L L), 陆建华(Lu J H), 朱源荣(Zhu Y R). 中华肿瘤杂志(Chinese Journal of Oncology), 2012, 34(7): 532—537
[21] 刘曙正(Liu S Z), 戴涤新(Dai D X), 连士勇(Lian S Y), 李变云(Li B Y). 中国肿瘤(China Cancer), 2008, 17(4): 278—280
[22] Liang X, Bi S, Yang W, Wang L, Cui G, Cui F, Zhang Y, Liu J, Gong X, Chen Y, Wang F, Zheng H, Guo J, Jia Z, Ma J, Wang H, Luo H, Li L, Jin S, Hadler S C, Wang Y. J. Infect. Dis., 2009, 200(1): 39—47
[23] Li J, Kang L N, Qiao Y L. Asian Pac. J. Cancer Prev., 2011, 12(5): 1149—1153
[24] Zhu F C, Li C G, Pan H X, Zhang Y J, Bi D, Tang H W, Datta S. Chin. J. Cancer, 2011, 30(8): 559—564
[25] 卫生部疾病预防控制局癌症早诊早治项目专家委员会 (Academic Board on Cancer Screening and Early Diagnosis, Bureau of Disease Control and Prevention, Ministry of Health)． 癌症早诊早治项目技术方案(2011年版)(Technical Scheme of Cancer Early Detection and Diagnosis, 2011)．北京:人民卫生 出版社(Beijing: People's Medical Publishing House), 2011
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