English
往期目录
新闻公告
More
化学进展 2009, Vol. 21 Issue (04): 696-704 前一篇   后一篇

• 综述与评论 •

液相微萃取研究与应用

王炎1*,张永梅2   

  1. (1.哈尔滨工业大学理学中心 哈尔滨 150001；2.哈尔滨工业大学应用化学系 哈尔滨 150001)
  • 收稿日期:2008-04-07 修回日期:2008-05-25 出版日期:2009-04-24 发布日期:2009-04-03
  • 通讯作者: 王炎 E-mail:wangy_msn@hotmail.com
下载PDF ( 2735 ) 引用
导出 被引次数 ( 139 | 12 )

Advances in Liquid-Phase Microextraction

Wang Yan1* ;  Zhang Yongmei2   

  1. (1. Science Research Center, Harbin Institute of Technology, Harbin 150001, China;2. Applied Chemistry Department, Harbin Institute of Technology, Harbin 150001, China)
  • Received:2008-04-07 Revised:2008-05-25 Online:2009-04-24 Published:2009-04-03
  • Contact: Wang Yan E-mail:wangy_msn@hotmail.com

液相微萃取是近年来新兴的一种微型化样品前处理技术。该技术集萃取、净化、浓缩于一体，具有溶剂耗量少、成本低廉、操作便捷、精确和灵敏度高的特点。本文全面深入地综述了液相微萃取的各种工作模式及其原理和特点，阐述了相关的联用分析技术和方法的适用性，归纳和分析了影响萃取的主要影响因素及优化的方法，突出了上述几方面中具有发展潜力的新进展，包括各种动态萃取模式与装置、 与其它技术联用的新策略、离子液体作为萃取溶剂等，详细总结了近年来液相微萃取技术在环境、药物和食品等分析领域中的应用情况。

关键词： 液相微萃取, 样品前处理, 萃取技术

Liquid-phase microextraction (LPME) is a newly developed miniaturized sample pretreatment technique. It integrates extraction, clean-up and concentration and has the advantages, such as, using less solvent, low cost, convenience, good accuracy and high sensitivity. In this paper the operation patterns of LPME, as well as their principles and features are comprehensively reviewed. The hyphenated methods related to LPME and their applicabilities are discussed. The main factors influencing LPME and the optimization methods are summarized and analyzed. And the research advances with further potentials in above aspects are emphasized, including the new dynamic LPME modes and apparatus, new strategies of combination use with other techniques, and using ionic liquids as solvents, etc. The recent applications of LPME in environment, medicine and food analysis are described in detail.

Contents
1 Introduction
2 Basic extraction patterns and principles
2.1 Single-drop microextraction(SDME)
2.2 Hollow fiber liquid-phase microextraction(HF-LPME)
2.3 Continuous-flow microextraction(CFME)
2.4 Dispersive liquid–liquid microextraction (DLLME)
3 LPME coupled with other techniques
3.1 Coupled with derivatization
3.2 Coupled with pressured hot water extraction
3.3 Coupled with analytical instruments
4 Parameters affecting LPME
4.1 Effect of extraction solvent
4.2 Effect of extraction temperature
4.3 Effect of salt and pH
4.4 Effect of stirring speed
5 Application of LPME
5.1 Environmental analysis
5.2 Medicine analysis
5.3 Food analysis
6 Conclusion

Key words: liquid-phase microextraction, sample pretreatment, extraction techniques

中图分类号: 

()

[ 1 ] 　Arthur C L , Pawliszyn J . Anal . Chem. , 1990 , 62 : 2145 —2148
[ 2 ] 　Psillakis E , Kalogerakis N. Trends Anal . Chem. , 2002 , 21 (1) :53 —63
[ 3 ] 　Jeannot M A , Cantwell F F. Anal . Chem. , 1996 , 68 : 2236 —2240
[ 4 ] 　He Y, Lee H K. Anal . Chem. , 1997 , 69 : 4634 —4640
[ 5 ] 　Shen G, Lee H K. Anal . Chem. , 2003 , 75 : 98 —103
[ 6 ] 　Demeestere K, Dewulf J , Witte B D , et al . J . Chromatogr. A ,2007 , 1153 : 130 —144
[ 7 ] 　Ye C L , Zhou Q X, Wang X M. J . Chromatogr. A , 2007 , 1139 :7 —13
[ 8 ] 　Yao J R , Xu H , LüL L , et al . Anal . Chim. Acta , 2008 , 1016(10) : 1 —7
[ 9 ] 　Wang Y, Kwok Y C , He Y, et al . Anal . Chem. , 1998 , 70 :4610 —4614
[10 ] 　Ouyang G F , Zhao W N , Pawliszyn J . J . Chromatogr. A , 2007 ,1138 : 47 —54
[11 ] 　Myung S W, Yoon S H , Kin M. Analyst , 2003 , 128 : 1443 —1446
[12 ] 　Mohammadi A , Alizadeh N. J . Chromatogr. A , 2006 , 1107 : 19 —28
[13 ] 　Pedersen-Bjergaard S , Rasmussen K E. Anal . Chem. , 1999 , 71 :2650 —2656
[14 ] 　Pedersen-Bjergaard S , Rasmussen K E. J Chromatogr. A , 2008 ,1184 : 132 —142
[15 ] 　赵汝松(Zhao R S) , 徐晓白(Xu X B) , 刘秀芬(Liu X F) . 分析化学(Chinese J . Anal . Chem. ) , 2004 , 9 : 1246 —1251
[16 ] 　Ho T S , Halvorsen T G, Pedersen-Bjergaard S , et al . J .Chromatogr. A , 2003 , 998 : 61 —72
[17 ] 　王春(Wang C) , 吴秋华(Wu Q H) , 王志(Wang Z) 等. 色谱(Chinese J . Chromatogr. ) , 2006 , 24 (5) : 516 —523
[18 ] 　Jiang X, Basheer C , Zhang J . J . Chromatogr. A , 2005 , 1087 :289 —294
[19 ] 　Jiang X, Lee H K. Anal . Chem. , 2004 , 76 : 5591 —5596
[20 ] 　Mahaveer B , Melwanki , Huang S D. Anal . Chim. Acta , 2006 ,555 : 139 —145
[21 ] 　Yu C H , Liu Q , Lan L D. J . Chromatogr. A , 2008 , 1188 : 124 —131
[22 ] 　Liu W P , Lee H K. Anal . Chem. , 2000 , 72 : 4462 —4467
[23 ] 　Xu L , Basheer C , Lee H K, et al . J . Chromatogr. A , 2007 , 1152 :184 —192
[24 ] 　Berijani S , Assadi Y, Anbia M, et al . J . Chromatogr. A , 2006 ,1123 : 1 —9
[25 ] 　Nagaraju D , Huang S D. J . Chromatogr. A , 2007 , 1161 : 89 —97
[26 ] 　Naseri M T, Hemmatkhah P , Hosseini M R , et al . Anal . Chim.Acta. , 2008 , 610 : 135 —141
[27 ] 　Liang P , Xu J , Li Q. Anal . Chim. Acta , 2008 , 609 : 53 —58
[28 ] 　Basheer C , Lee H K. J . Chromatogr. A , 2004 , 1057 : 163 —169
[29 ] 　Varanusupakul P , Vora-adisak N , Pulpoka B. Anal . Chim. Acta ,2007 , 598 : 82 —86
[30 ] 　Deng C H , Yao N , Wang A Q , et al . Anal . Chim. Acta , 2005 ,536 : 237 —244
[31 ] 　Deng C H , Yang X H , Zhang XM. Talanta , 2005 , 68 : 6 —11
[32 ] 　Rasmussen K E , Pedersen-Bjergaard S , Krogh M, et al . J .Chromatogr. A , 2000 , 873 : 3 —11
[33 ] 　罗明标(Luo MB) , 刘维(Liu W) , 李伯平(Li B P) . 分析化学(Chinese J . Anal . Chem. ) , 2007 , 35 (7) : 1071 —1077
[34 ] 　吴英亮(Wu YL) , 江祖成(Jiang Z C) , 胡斌(Hu B) . 高等学校化学学报(Chem. J . Chinese Universities) , 2003 , 24 (10) :1793 —1794
[35 ] 　Müller S , Moder M, Schrader S , et al . J . Chromatgr. A , 2003 ,985 : 99 —106
[36 ] 　Andersen S , Halvorsen T G, Pedersn-Bjergaard S , et al . Biomed.Anal . , 2003 , 33 (2) : 263 —273
[37 ] 　De Jager L S , Andrews A R J . Analyst , 2001 , 126 (8) : 1298 —1300
[38 ] 　Yan C H , Wu H F. Rapid Commun. Mass Spectrom. , 2004 , 18 :3015 —3018
[39 ] 　Mahaveer B , Melwanki , Huang S D. J . Sep. Sci . , 2006 , 29 :2078 —2084
[40 ] 　Liu J F , Jiang G B , Chi Y G, et al . Anal . Chem. , 2003 , 21 :5870 —5876
[41 ] 　Liu J F , Chi Y G, Jiang G B , et al . J . Chromatogr. A , 2004 ,1026 : 143 —147
[42 ] 　丁琪(Ding Q) , 乐长高(Le C G) . 化工时刊(Chemical Industry Times) , 2006 , 20 (7) : 64 —67
[43 ] 　Batlle R , Nerin C. J . Chromatogr. A , 2004 , 1045 : 29 —35
[44 ] 　孙世豪(Sun S H) , 宗永立(Zong YL) , 谢剑平(Xie J P) . 烟草化学(Tobacco Chemistry) , 2006 , 5 : 41 —45
[45 ] 　Yadollah Y, Mohammad H , Majid H H , et al . Talanta , 2004 , 62 :265 —270
[46 ] 　Shahab S F , Yadollah Y, Naader B. Anal . Chim. Acta , 2003 ,489 : 21 —31
[47 ] 　Hou L , Lee H K. J . Chromatogr. A , 2004 , 1038 : 37 —42
[48 ] 　罗明标(Luo MB) ,杨新磊(Yang XL) ,曹维鹏(Cao W P) . 环境污染与防治( Environmental Pollution and Control) , 2006 , 2 :1 —9
[49 ] 　Lambropoulou D A , Konstantinou I K, Albanis TA. J . Chromatogr.A , 2007 , 1152 : 70 —96
[50 ] 　Pedersen-Bjergaard S , Rasmussen K E. J . Chromatogr. B , 2005 ,817 : 3 —12
[51 ] 　Deng C H , Liu N , Gao M X. J . Chromatogr. A , 2007 , 1153 :90 —96
[52 ] 　Bicchi C , Cordero C , Liberto E. J . Chromatogr. A , 2008 , 1184 :220 —233
[53 ] 　王炎(Wang Y) , 张永梅(Zhang YM) , 梁志华(Liang Z H) . 分析试验室(Chinese J . Anal . Lab. ) , 2008 , 27 (3) : 115 —118
[54 ] 　Sun S H , Cheng Z H , Xie J P , et al . Rapid Commun. Mass Spectrum. , 2005 , 19 (8) : 1 —6
[55 ] 　Ye C L , Zhou Q X, Wang X M. Anal . Chim. Acta , 2006 , 572 :165 —171
[56 ] 　Xia L B , Wu YL , Hu B. J . Mass Spectrom. , 2007 , 42 : 803 —810
[57 ] 　Shioji H , Tsunoi S , Harino H , et al . J . Chromatogr. A , 2004 ,1048 : 81 —88
[58 ] 　Pan HJ , Ho W H. Anal . Chim. Acta , 2004 , 527 : 61 —67
[59 ] 　Psillakis E , Mantzavinos D , Kalogerakis N. Anal . Chim. Acta ,2004 , 501 : 3 —10
[60 ] 　Basheer C , Balacubramamian R , Lee H K. J . Chromatogr. A ,2003 , 1016 : 11 —20
[61 ] 　周建科(Zhou J K) , 李路华(Li L H) , 韩康(Han K) 等. 分析试验室(Chinese J . Anal . Lab. ) , 2006 : 25 (5) : 53 —55
[62 ] 　谢洪学(Xie H X) , 何丽君(He L J ) , 伍艳(Wu Y) . 分析化学(Chinese J . Anal . Chem. ) , 2007 , 35 (2) : 187 —190
[63 ] 　Ye C L , Zhou Q X, Wang X M, et al . J . Sep. Sci . , 2007 , 30 :42 —47
[64 ] 　Xu J , Liang P , Zhang T Z. Anal . Chim. Acta , 2007 , 597 : 1 —5
[65 ] 　杨秀敏(Yang XM) , 王志(Wang Z) , 王春(Wang C) 等. 色谱(Chinese J . Chromatogr. ) , 2007 , 25 (3) : 362 —366
[66 ] 　Wu H F , Lin C H. Rapid Commun. Mass Spectrom. , 2006 , 20 :2511 —2515
[67 ] 　de Oliveira A R M, Cardoso C D , Bonato P S. Electrophoresis ,2007 , 28 : 1081 —1091
[68 ] 　Basheer C , Lee H K, Obbard J P. J . Chromatogr. A , 2004 , 1022 :161 —169
[69 ] 　康绍英(Kang S Y) , 王海波(Wang HB) , 马铭(Ma M) 等. 分析化学(Chinese J . Anal . Chem. ) , 2004 , 32 (11) : 1421 —1425
[70 ] 　肖小华(Xiao X H) , 尹怡(Yin Y) , 胡玉玲(Hu YL) 等. 色谱(Chinese J . Chromatogr. ) , 2007 , 25 (2) : 234 —237
[71 ] 　杨新磊(Yang XL) , 罗明标(Luo M B) , 丁健桦(Ding J H) .分析化学(Chinese J . Anal . Chem. ) , 2007 , 35 (2) : 171 —175
[72 ] 　王晓飞(Wang X F) , 刘俊亭(Liu J T) , 王妍(Wang Y) . 色谱(Chinese J . Chromatogr. ) , 2006 , 24 (6) : 641 —644
[73 ] 　朱丹(Zhu D) , 孟品佳(Meng P J ) , 何洪源(He H Y) . 色谱(Chinese J . Chromatogr. ) , 2007 , 25 (1) : 16 —20
[74 ] 　张成功(Zhang C G) , 赵倩(Zhao Q) , 陈波(Chen B) 等. 色谱(Chinese J . Chromatogr. ) , 2007 , 25 (5) : 641 —645
[75 ] 　Mahaveer B , Melwanki , Huang S D , et al . Talanta , 2007 , 72 :373 —377
[76 ] 　张朝辉(Zhang C H) , 康绍英( Kang S Y) , 许敏洁(Xu MJ )等. 色谱(Chinese J . Chromatogr. ) , 2005 , 23 : 358 —361
[77 ] 　Tsai T F , Lee M R. Talanta , 2008 , 75 : 658 —665
[78 ] 　Yang C L , Guo L Y, Liu X Y. J . Chromatogr. A , 2007 , 1164 :56 —64
[79 ] 　Ebrahimzadeh H , Yamini Y, Sedighi A. J . Chromatogr. B , 2008 ,863 : 229 —234
[80 ] 　Magalhaes I R S , Bonato P S. J . Pharmaceut . Biomed. Anal . ,2008 , 46 : 929 —936
[81 ] 　Chiang J S , Huang S D. J . Chromatogr. A , 2008 , 1185 : 19 —22
[82 ] 　Santana FJ M, Bonato P S. Anal . Chim. Acta , 2008 , 606 : 80 —91
[83 ] 　Zhao R S , Lao WJ , Xu X B. Talanta , 2004 , 62 : 751 —756
[84 ] 　Gonzalez-Penas E , Leacje C , Viscarret M, et al . J . Chromatogr. A ,2004 , 1025 : 163 —168
[85 ] 　Psillakis E , Kalogerakis N. J . Chromatogr. A , 2003 , 999 : 145 —153
[86 ] 　Kaykhaii M, Rahmani M. J . Sep. Sci . , 2007 , 30 : 573 —578
[87 ] 　李玫瑰(Li M G) , 李元星(Li Y X) , 毛丽秋(Mao L Q) . 色谱(Chinese J . Chromatogr. ) , 2007 , 25 (1) : 35 —38
[88 ] 　李敏霞(Li M X) , 吴京洪(Wu J H) , 邹世春(Zou S C) 等. 分析化学(Chinese J . Anal . Chem. ) , 2007 , 35 (8) : 1116 —1120
[89 ] 　杨新磊(Yang XL) , 罗明标(Luo M B) , 丁健桦(Ding J H) .分析测试学报(J . Instrumental Anal . ) , 2007 , 26 (5) : 714 —717
[90 ] 　Sun S H , Xie J P , Xie F W. J . Chromatogr. A , 2008 , 1179 :89 —95
[1] 刘育坚, 刘智敏, 许志刚, 李攻科. 搅拌棒吸附萃取技术[J]. 化学进展, 2020, 32(9): 1334-1343.
[2] 宋志花, 李盛红, 杨刚强, 周娜, 陈令新. 人参皂苷类化合物样品前处理及分析检测[J]. 化学进展, 2020, 32(2/3): 239-248.
[3] 韩强, 王宗花, 张晓琼, 丁明玉. 石墨烯及其复合材料在样品前处理中的应用[J]. 化学进展, 2014, 26(05): 820-833.
[4] 许志刚*, 刘智敏, 杨保民, 字富庭. 替代模板分子印迹技术在样品前处理中的应用[J]. 化学进展, 2012, 24(08): 1592-1598.
[5] 李瑞萍,张艺,黄应平. 环境样品中四环素类抗生素的检测技术*[J]. 化学进展, 2008, 20(12): 2075-2082.
[6] 何翊,黄骏雄,贾金平. 固相微萃取技术与环境样品前处理[J]. 化学进展, 1998, 10(01): 74-.
阅读次数
全文


摘要

液相微萃取研究与应用